Universidad de Investigacion para la Generacion y Sintesis de Evidencia en Salud, Universidad San Ignacio de Loyola 2 articles published in JoVE Neuroscience Using Home-based, Remotely Supervised, Transcranial Direct Current Stimulation for Phantom Limb Pain Kevin Pacheco-Barrios*1,2, Daniela Martinez-Magallanes*1, Cristina Xicota Naqui1,3, Marianna Daibes1, Elly Pichardo1, Alejandra Cardenas-Rojas1, David Crandell4, Anahita Dua5, Abhishek Datta6,7, Wolnei Caumo8,9,10, Felipe Fregni1 1Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital, Massachusetts General Hospital, Harvard Medical School, 2Vicerrectorado de Investigación, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, 3Nursing Department, Universitat Internacional de Catalunya, 4Spaulding Rehabilitation Hospital, Harvard Medical School, 5Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Harvard Medical School, 6Research and Development, Soterix Medical, 7City College of New York, 8Post-Graduate Program in Medical Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), 9Laboratory of Pain & Neuromodulation, Hospital de Clinicas de Porto Alegre (HCPA), 10Pain and Palliative Care Service, Hospital de Clinicas de Porto Alegre (HCPA) The goal of this study is to describe a protocol for the home-based delivery of remotely supervised transcranial direct current stimulation (RS-tDCS) conserving the standard procedures of in-clinic practice, including safety, reproducibility, and tolerability. The participants included will be patients with phantom limb pain (PLP). Neuroscience Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition Ingrid Rebello-Sanchez1, Joao Parente1, Kevin Pacheco-Barrios1,2, Anna Marduy1, Danielle Carolina Pimenta1, Daniel Lima1, Eric Slawka1, Alejandra Cardenas-Rojas1, Gleysson Rodrigues Rosa1, Kamran Nazim3, Abhishek Datta3,4, Felipe Fregni1 1Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, 2Universidad de Investigación para la Generación y Síntesis de Evidencia en Salud, Universidad San Ignacio de Loyola, 3Research and Development, Soterix Medical, 4City College of New York Contralateral silent period (cSP) assessment is a promising biomarker to index cortical excitability and treatment response. We demonstrate a protocol to assess cSP intended for studying M1 corticospinal inhibition of upper and lower limbs.
