Karthik Nagapudi

Publications

• High-throughput Screening and Scale-up of Cocrystals Using Resonant Acoustic Mixing
  International Journal of Pharmaceutics. Apr, 2017  |   Pubmed ID: 28229947
• Humidity Induced Phase Transformation of Poloxamer 188 and Its Effect on Physical Stability of Amorphous Solid Dispersion of AMG 579, a PDE10A Inhibitor
  International Journal of Pharmaceutics. Apr, 2017  |   Pubmed ID: 28163226
• Control Strategies for Drug Product Continuous Direct Compression-State of Control, Product Collection Strategies, and Startup/Shutdown Operations for the Production of Clinical Trial Materials and Commercial Products
  Journal of Pharmaceutical Sciences. Apr, 2017  |   Pubmed ID: 28069357
• A Rational Approach Towards Development of Amorphous Solid Dispersions: Experimental and Computational Techniques
  International Journal of Pharmaceutics. Mar, 2017  |   Pubmed ID: 28063904
• Application of (19)  F Time-domain NMR to Measure Content in Fluorine-containing Drug Products
  Magnetic Resonance in Chemistry : MRC. Jun, 2016  |   Pubmed ID: 25773191
• Investigation of Phase Mixing in Amorphous Solid Dispersions of AMG 517 in HPMC-AS Using DSC, Solid-State NMR, and Solution Calorimetry
  Molecular Pharmaceutics. Nov, 2015  |   Pubmed ID: 26457879
• Conformational Isomerism in Solid State of AMG 853--structure Studies Using Solid-state Nuclear Magnetic Resonance and X-ray Diffraction
  Journal of Pharmaceutical Sciences. Jul, 2015  |   Pubmed ID: 25912152
• Amorphous Solid Dispersions: a Robust Platform to Address Bioavailability Challenges
  Therapeutic Delivery. Feb, 2015  |   Pubmed ID: 25690090
• Sorbitol Crystallization-induced Aggregation in Frozen MAb Formulations
  Journal of Pharmaceutical Sciences. Feb, 2015  |   Pubmed ID: 25219372
• Application of Twin Screw Extrusion to the Manufacture of Cocrystals: Scale-up of AMG 517-sorbic Acid Cocrystal Production
  Faraday Discussions. 2014  |   Pubmed ID: 25406487
• Structural Studies of a Non-stoichiometric Channel Hydrate Using High Resolution X-ray Powder Diffraction, Solid-state Nuclear Magnetic Resonance, and Moisture Sorption Methods
  Journal of Pharmaceutical Sciences. Sep, 2014  |   Pubmed ID: 24470123
• Effect of PH and Excipients on Structure, Dynamics, and Long-term Stability of a Model IgG1 Monoclonal Antibody Upon Freeze-drying
  Pharmaceutical Research. Apr, 2013  |   Pubmed ID: 23184227
• Crystal Structure Study and Investigation of Solid-state Cyclization for AMG 222, a Channel Hydrate
  International Journal of Pharmaceutics. Jan, 2013  |   Pubmed ID: 23182974
• High-throughput 96-well Solvent Mediated Sonic Blending Synthesis and On-plate Solid/solution Stability Characterization of Pharmaceutical Cocrystals
  International Journal of Pharmaceutics. Jan, 2013  |   Pubmed ID: 23178596
• Application of Twin Screw Extrusion in the Manufacture of Cocrystals, Part I: Four Case Studies
  Pharmaceutics. Aug, 2011  |   Pubmed ID: 24310598
• Manufacture and Performance Evaluation of a Stable Amorphous Complex of an Acidic Drug Molecule and Neusilin
  Journal of Pharmaceutical Sciences. Aug, 2011  |   Pubmed ID: 21520086
• Selective and Potent Raf Inhibitors Paradoxically Stimulate Normal Cell Proliferation and Tumor Growth
  Molecular Cancer Therapeutics. Aug, 2010  |   Pubmed ID: 20663930
• Fast Surface Crystallization of Amorphous Griseofulvin Below T G
  Pharmaceutical Research. Aug, 2010  |   Pubmed ID: 20414704
• Manufacture of Pharmaceutical Co-crystals Using Twin Screw Extrusion: a Solvent-less and Scalable Process
  Journal of Pharmaceutical Sciences. Apr, 2010  |   Pubmed ID: 19774652
• Quantification of Compaction-induced Crystallinity Reduction of a Pharmaceutical Solid Using 19F Solid-state NMR and Powder X-ray Diffraction
  Drug Development and Industrial Pharmacy. Aug, 2009  |   Pubmed ID: 19360510
• Alterations in Physical Cross-linking Modulate Mechanical Properties of Two-phase Protein Polymer Networks
  Biomacromolecules. Nov-Dec, 2005  |   Pubmed ID: 16283724
• Viscoelastic and Mechanical Behavior of Recombinant Protein Elastomers
  Biomaterials. Aug, 2005  |   Pubmed ID: 15763249
• Photo-cross-linking of Type I Collagen Gels in the Presence of Smooth Muscle Cells: Mechanical Properties, Cell Viability, and Function
  Biomacromolecules. Jul-Aug, 2003  |   Pubmed ID: 12857069