University Hospital 1 article published in JoVE Genetics Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System Anni Määttä*1, Niko Järveläinen*1, Jaakko Lampela1, Seppo Ylä-Herttuala1,2 1A.I. Virtanen Institute, University of Eastern Finland, 2Heart Center and Gene Therapy Unit, Kuopio University Hospital The present protocol describes a large animal exercise test model to assess the functional capacity of the cardiovascular system for evaluating the efficiency of new therapies in the preclinical setting. It is comparable to a clinical exercise test.