Cancer Center Amsterdam 4 articles published in JoVE Medicine Robotic D3 Partial Duodenal Resection with Primary Side-to-Side Anastomosis Roberto Maria Montorsi1,2,3, Sofia Xenaki1,2,4, Sebastiaan Festen5, Paul Fockens2,6, Barbara A. J. Bastiaansen2,6, Freek Daams2,7, Olivier R. Busch1,2, M. G. Besselink1,2, HPB-Amsterdam, 1Amsterdam UMC, Department of Surgery, University of Amsterdam, 2Cancer Center Amsterdam, 3Department of General and Pancreatic Surgery, The Pancreas Institute, University of Verona Hospital Trust, 4Department of General Surgery, University Hospital of Heraklion Crete, 5Department of Surgery, OLVG, 6Amsterdam UMC, Department of Gastroenterology, University of Amsterdam, 7Amsterdam UMC, Department of Surgery, Vrije Universiteit This protocol presents a case of a robotic partial duodenal resection with primary side-to-side duodeno-jejunal reconstruction in a patient with a 5 cm duodenal stenosis. This is done at the third duodenal segment (D3) after an endoscopic mucosal resection (EMR) for a duodenal polyp. Medicine Robotic Left Hepatectomy using Indocyanine Green Fluorescence Imaging for an Intrahepatic Complex Biliary Cyst Burak Görgec1,2, Babs M. Zonderhuis2,3, Marc G. Besselink1,2, Joris Erdmann1,2,3, Geert Kazemier2,3, Rutger-Jan Swijnenburg1,2,3 1Department of Surgery, Amsterdam UMC, location University of Amsterdam, 2Cancer Center Amsterdam, 3Department of Surgery, Amsterdam UMC, location Vrije Universiteit Robotic liver surgery has gained more acceptance as a feasible, safe, and effective procedure for the treatment of both benign and malignant indications. However, robotic left hepatectomy is still technically demanding. We describe our surgical technique of a robotic left hepatectomy using indocyanine green fluorescence imaging for a large biliary cyst. Cancer Research Robotic Pancreatoduodenectomy for Pancreatic Head Cancer: a Case Report of a Standardized Technique Maurice J. W. Zwart*1,2, Leia R. Jones*1,2,3, Melissa E. Hogg4, Johanna A. M. G. Tol1,2, Mohammad Abu Hilal3, Freek Daams5, Sebastiaan Festen6, Olivier R. Busch1,2, Marc G. Besselink1,2, HPB-Amsterdam, 1Department of Surgery, Amsterdam, the Netherlands, Amsterdam UMC, location University of Amsterdam, 2Cancer Center Amsterdam, the Netherlands, 3Department of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, 4Department of Surgery, Northshore University Health System, 5Department of Surgery, Amsterdam UMC, Vrije Universiteit, Cancer Center Amsterdam, 6Department of Surgery, OLVG Robotic pancreatoduodenctomy (RPD) has been highly standardized in recent years and may be used in selected patients with pancreatic head cancer, including those with a replaced right hepatic artery. This case report describes a standardized and reproducible technique for RPD, which includes the approach of the Dutch LAELAPS-3 training program to an aberrant vasculature. Neuroscience A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents Rianne Haumann*1,2, Elvin ’t Hart*2, Marc P. P. Derieppe2, Helena C. Besse3, Gertjan J. L. Kaspers1,2, Eelco Hoving2, Dannis G. van Vuurden1,2, Esther Hulleman1,2, Mario Ries3 1Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, 2Princess Máxima Center for Pediatric Oncology, 3Imaging Division, Utrecht University The blood-brain barrier (BBB) can be temporarily disrupted with microbubble-mediated focused ultrasound (FUS). Here, we describe a step-by-step protocol for high-throughput BBB opening in vivo using a modular FUS system accessible for non-ultrasound experts.