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Journal
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Cancer Research
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Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors
/
Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
JoVE Journal
Cancer Research
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JoVE Journal
Cancer Research
Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor
Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
Genome-Scale Screening to Identify and Compare Therapeutic Targets in Tumors
DOI:
10.3791/65430-v
•
01:41 min
•
August 25, 2023
•
Brittany Turner-Ivey
,
Jody Fromm Longo
,
Dorea P. Jenkins
,
Stephen T. Guest
,
Steven L. Carroll
2
1
Hollings Cancer Center
,
Medical University of South Carolina
,
2
Department of Pathology and Laboratory Medicine
,
Medical University of South Carolina
,
3
Department of Computational Medicine and Bioinformatics
,
University of Michigan, Ann Arbor
Tags
Genetic Profiling
Genome-scale Dropout Screening
Malignant Peripheral Nerve Sheath Tumors
NF1
Unbiased Screening
Single-cell Sequencing
Bioinformatics
ErbB3
Lysophosphatidic Acid Receptor 3
Schwann Cells
Neurofibromatosis Type 1
Targeted Therapies
Functional Genomic Screening
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