Christopher Hughes: An in vitro model for the Study of Angiogenesis (Interview)
Summary
Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro. He explains the importance of fibroblasts that secrete a critical, yet unidentified, soluble factor that allow endothelial cells to form vessels in culture that branch, form proper lumens, and undergo anastamosis.
Abstract
Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro. He explains the importance of fibroblasts that secrete a critical, yet unidentified, soluble factor that allow endothelial cells to form vessels in culture that branch, form proper lumens, and undergo anastamosis.
Disclosures
The authors have nothing to disclose.
Cite This Article
Hughes, C. C. Christopher Hughes: An in vitro model for the Study of Angiogenesis (Interview). J. Vis. Exp. (3), e175, doi:10.3791/175 (2007).