David Brown

Publications

• Comparison of In Vitro Approaches to Assess the Antibacterial Effects of Nanomaterials
  Journal of Functional Biomaterials. Nov, 2022  |   Pubmed ID: 36412895
• Transgenic Zebrafish Larvae As a Non-rodent Alternative Model to Assess Pro-inflammatory (neutrophil) Responses to Nanomaterials
  Nanotoxicology. Apr, 2022  |   Pubmed ID: 35797989
• An in Vitro Assessment of the Toxicity of Two-dimensional Synthetic and Natural Layered Silicates
  Toxicology in Vitro : an International Journal Published in Association with BIBRA. Feb, 2022  |   Pubmed ID: 34801683
• Acute Hazard Assessment of Silver Nanoparticles Following Intratracheal Instillation, Oral and Intravenous Injection Exposures
  Nanotoxicology. Dec, 2021  |   Pubmed ID: 35015612
• Time Dependent Impact of Copper Oxide Nanomaterials on the Expression of Genes Associated with Oxidative Stress, Metal Binding, Inflammation and Mucus Secretion in Single and Co-culture Intestinal in Vitro Models
  Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2021  |   Pubmed ID: 33839236
• Neutrophil Activation by Nanomaterials : Comparing Strengths and Limitations of Primary Human Cells with Those of an Immortalized (HL-60) Cell Line
  Nanotoxicology. Feb, 2021  |   Pubmed ID: 33272088
• Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes
  ACS Nano. Apr, 2020  |   Pubmed ID: 32167743
• Importance of Surface Coating to Accumulation Dynamics and Acute Toxicity of Copper Nanomaterials and Dissolved Copper in Daphnia Magna
  Environmental Toxicology and Chemistry. Feb, 2020  |   Pubmed ID: 31610609
• The Variances in Cytokine Production Profiles from Non- or Activated THP-1, Kupffer Cell and Human Blood Derived Primary Macrophages Following Exposure to Either Alcohol or a Panel of Engineered Nanomaterials
  PloS One. 2019  |   Pubmed ID: 31393970
• The Mechanism-based Toxicity Screening of Particles with Use in the Food and Nutrition Sector Via the ToxTracker Reporter System
  Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2019  |   Pubmed ID: 31279906
• Using 3D Gastrointestinal Tract in Vitro Models with Microfold Cells and Mucus Secreting Ability to Assess the Hazard of Copper Oxide Nanomaterials
  Journal of Nanobiotechnology. May, 2019  |   Pubmed ID: 31113462
• The Importance of Inter-individual Kupffer Cell Variability in the Governance of Hepatic Toxicity in a 3D Primary Human Liver Microtissue Model
  Scientific Reports. May, 2019  |   Pubmed ID: 31086251
• The Influence of Organic Modification on the Cytotoxicity of Clay Particles to Keratinocytes, Hepatocytes and Macrophages; an Investigation Towards the Safe Use of Polymer-clay Nanocomposite Packaging
  Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Apr, 2019  |   Pubmed ID: 30797875
• Assessing the Bioactivity of Crystalline Silica in Heated High-temperature Insulation Wools
  Inhalation Toxicology. 2018  |   Pubmed ID: 30328741
• Corrigendum to "the Role of Intracellular Redox Imbalance in Nanomaterial Induced Cellular Damage and Genotoxicity: A Review"
  Environmental and Molecular Mutagenesis. Apr, 2018  |   Pubmed ID: 29423917
• Adoption of in Vitro Systems and Zebrafish Embryos As Alternative Models for Reducing Rodent Use in Assessments of Immunological and Oxidative Stress Responses to Nanomaterials
  Critical Reviews in Toxicology. Mar, 2018  |   Pubmed ID: 29239234
• Transcriptional Profiling Reveals Gene Expression Changes Associated with Inflammation and Cell Proliferation Following Short-term Inhalation Exposure to Copper Oxide Nanoparticles
  Journal of Applied Toxicology : JAT. Mar, 2018  |   Pubmed ID: 29094763
• A Flow Cytometry-based Method for the Screening of Nanomaterial-induced Reactive Oxygen Species Production in Leukocytes Subpopulations in Whole Blood
  Basic & Clinical Pharmacology & Toxicology. Jan, 2018  |   Pubmed ID: 28691406
• Impact of Copper Oxide Nanomaterials on Differentiated and Undifferentiated Caco-2 Intestinal Epithelial Cells; Assessment of Cytotoxicity, Barrier Integrity, Cytokine Production and Nanomaterial Penetration
  Particle and Fibre Toxicology. Aug, 2017  |   Pubmed ID: 28835236
• The Effect of Aluminium and Sodium Impurities on the in Vitro Toxicity and Pro-inflammatory Potential of Cristobalite
  Environmental Research. Nov, 2017  |   Pubmed ID: 28802207
• Surfactants from Itaconic Acid: Toxicity to HaCaT Keratinocytes in Vitro, Micellar Solubilization, and Skin Permeation Enhancement of Hydrocortisone
  International Journal of Pharmaceutics. May, 2017  |   Pubmed ID: 28356226
• Organ Burden and Pulmonary Toxicity of Nano-sized Copper (II) Oxide Particles After Short-term Inhalation Exposure
  Nanotoxicology. Oct, 2016  |   Pubmed ID: 27132941
• Exploring the Cellular and Tissue Uptake of Nanomaterials in a Range of Biological Samples Using Multimodal Nonlinear Optical Microscopy
  Nanotechnology. Dec, 2015  |   Pubmed ID: 26584818
• Multi-walled Carbon Nanotube Induced Frustrated Phagocytosis, Cytotoxicity and Pro-inflammatory Conditions in Macrophages Are Length Dependent and Greater Than That of Asbestos
  Toxicology in Vitro : an International Journal Published in Association with BIBRA. Oct, 2015  |   Pubmed ID: 26086123
• Mechanism of Neutrophil Activation and Toxicity Elicited by Engineered Nanomaterials
  Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2015  |   Pubmed ID: 25962642
• Serum Enhanced Cytokine Responses of Macrophages to Silica and Iron Oxide Particles and Nanomaterials: a Comparison of Serum to Lung Lining Fluid and Albumin Dispersions
  Journal of Applied Toxicology : JAT. Nov, 2014  |   Pubmed ID: 24737200
• The Role of Kupffer Cells in the Hepatic Response to Silver Nanoparticles
  Nanotoxicology. Aug, 2014  |   Pubmed ID: 24344730
• Investigating the Relationship Between Nanomaterial Hazard and Physicochemical Properties: Informing the Exploitation of Nanomaterials Within Therapeutic and Diagnostic Applications
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2012  |   Pubmed ID: 22940205