Gábor Mező MTA-ELTE Research Group of Peptide Chemistry Eötvös Loránd University Biography Publications Institution JoVE Articles Gábor Mező has not added a biography. If you are Gábor Mező and would like to personalize this page please email our Author Liaison for assistance. Publications Cellular Uptake Mechanism of Cationic Branched Polypeptides with Poly[l-Lys] Backbone ACS Combinatorial Science. Mar, 2017 | Pubmed ID: 28276242 Synthesis, Characterization and Systematic Comparison of FITC-labelled GnRH-I, -II and -III Analogues on Various Tumour Cells Journal of Peptide Science : an Official Publication of the European Peptide Society. Aug, 2016 | Pubmed ID: 27443981 Improved in Vivo Antitumor Effect of a Daunorubicin - GnRH-III Bioconjugate Modified by Apoptosis Inducing Agent Butyric Acid on Colorectal Carcinoma Bearing Mice Investigational New Drugs. Aug, 2016 | Pubmed ID: 27146514 A Double-Clicking Bis-Azide Fluorogenic Dye for Bioorthogonal Self-Labeling Peptide Tags Chemistry (Weinheim an Der Bergstrasse, Germany). Apr, 2016 | Pubmed ID: 27010966 [Studying the Tumor Growth Inhibitory Effect of Modified GnRH-III-anthracycline Bioconjugates in Subcutaneous Vs. Orthotopic Models in Vivo] Magyar Onkologia. Dec, 2015 | Pubmed ID: 26665191 Comparative in Vitro Biological Evaluation of Daunorubicin Containing GnRH-I and GnRH-II Conjugates Developed for Tumor Targeting Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2015 | Pubmed ID: 25908176 Modification of Daunorubicin-GnRH-III Bioconjugates with Oligoethylene Glycol Derivatives to Improve Solubility and Bioavailability for Targeted Cancer Chemotherapy Biopolymers. May, 2015 | Pubmed ID: 25753049 Antimycobacterial Activity of Peptide Conjugate of Pyridopyrimidine Derivative Against Mycobacterium Tuberculosis in a Series of in Vitro and in Vivo Models Tuberculosis (Edinburgh, Scotland). Jun, 2015 | Pubmed ID: 25728610 Development of Cyclic NGR Peptides with Thioether Linkage: Structure and Dynamics Determining Deamidation and Bioactivity Journal of Medicinal Chemistry. Feb, 2015 | Pubmed ID: 25646854 In Vivo Imaging of Aminopeptidase N (CD13) Receptors in Experimental Renal Tumors Using the Novel Radiotracer (68)Ga-NOTA-c(NGR) European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Mar, 2015 | Pubmed ID: 25592229 Protein Expression Profile of HT-29 Human Colon Cancer Cells After Treatment with a Cytotoxic Daunorubicin-GnRH-III Derivative Bioconjugate PloS One. 2014 | Pubmed ID: 24718594 Leishmania Braziliensis: Cytotoxic, Cytostatic and Chemotactic Effects of Poly-lysine-methotrexate-conjugates Experimental Parasitology. Sep, 2013 | Pubmed ID: 23816643 Binding of New Cationic Porphyrin-tetrapeptide Conjugates to Nucleoprotein Complexes Biophysical Chemistry. Jul-Aug, 2013 | Pubmed ID: 23603112 Synthesis, Enzymatic Stability and in Vitro Cytostatic Effect of Daunorubicin-GnRH-III Derivative Dimers Bioorganic & Medicinal Chemistry Letters. Apr, 2013 | Pubmed ID: 23434423 NIR Mega-Stokes Fluorophores for Bioorthogonal Labeling and Energy Transfer Systems--an Efficient Quencher for Daunomycin Chemistry, an Asian Journal. Feb, 2013 | Pubmed ID: 23225500 Investigation on Chemotactic Drug Targeting (chemotaxis and Adhesion) Inducer Effect of GnRH-III Derivatives in Tetrahymena and Human Leukemia Cell Line Journal of Peptide Science : an Official Publication of the European Peptide Society. Jan, 2013 | Pubmed ID: 23208929 A Novel Cyclic RGD-containing Peptide Polymer Improves Serum-free Adhesion of Adipose Tissue-derived Mesenchymal Stem Cells to Bone Implant Surfaces Journal of Materials Science. Materials in Medicine. Feb, 2013 | Pubmed ID: 23135412 LGnRH-III -- a Promising Candidate for Anticancer Drug Development Protein and Peptide Letters. Apr, 2013 | Pubmed ID: 23016589 Enhanced Cellular Uptake and in Vitro Antitumor Activity of Short-chain Fatty Acid Acylated Daunorubicin-GnRH-III Bioconjugates European Journal of Medicinal Chemistry. Oct, 2012 | Pubmed ID: 22967796 Enhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation Bioconjugate Chemistry. May, 2012 | Pubmed ID: 22515329 GnRH-III Based Multifunctional Drug Delivery Systems Containing Daunorubicin and Methotrexate European Journal of Medicinal Chemistry. Jun, 2012 | Pubmed ID: 22480495 In-vivo Antitumour Effect of Daunorubicin-GnRH-III Derivative Conjugates on Colon Carcinoma-bearing Mice Anti-cancer Drugs. Jan, 2012 | Pubmed ID: 21915040 Design, Synthesis, in Vitro Stability and Cytostatic Effect of Multifunctional Anticancer Drug-bioconjugates Containing GnRH-III As a Targeting Moiety Biopolymers. 2012 | Pubmed ID: 21509746 Isolation of Radial Glia-like Neural Stem Cells from Fetal and Adult Mouse Forebrain Via Selective Adhesion to a Novel Adhesive Peptide-conjugate PloS One. 2011 | Pubmed ID: 22163310 Anthracycline-GnRH Derivative Bioconjugates with Different Linkages: Synthesis, in Vitro Drug Release and Cytostatic Effect Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2011 | Pubmed ID: 21864594 Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4 Bioconjugate Chemistry. Jul, 2011 | Pubmed ID: 21668011 Syntheses and DNA Binding of New Cationic Porphyrin-tetrapeptide Conjugates Biophysical Chemistry. Apr, 2011 | Pubmed ID: 21402435 In Vitro Degradation and Antitumor Activity of Oxime Bond-linked Daunorubicin-GnRH-III Bioconjugates and DNA-binding Properties of Daunorubicin-amino Acid Metabolites Amino Acids. Jul, 2011 | Pubmed ID: 20953647 Efficient Synthesis of an (aminooxy) Acetylated-somatostatin Derivative Using (aminooxy)acetic Acid As a 'carbonyl Capture' Reagent Journal of Peptide Science : an Official Publication of the European Peptide Society. Jan, 2011 | Pubmed ID: 20812368 Daunomycin-polypeptide Conjugates with Antitumor Activity Biochimica Et Biophysica Acta. Dec, 2010 | Pubmed ID: 20659420 [Role of Iron Metabolism-regulator Hepcidin in Perinatal Iron Homeostasis] Orvosi Hetilap. Jan, 2010 | Pubmed ID: 20061265 Receptor-mediated Tumor Targeting Based on Peptide Hormones Expert Opinion on Drug Delivery. Jan, 2010 | Pubmed ID: 19947889 Luteinizing Hormone-releasing Hormone Antagonists Expert Opinion on Therapeutic Patents. Dec, 2009 | Pubmed ID: 19939192 Probing the Activity of Matrix Metalloproteinase II with a Sequentially Click-labeled Silica Nanoparticle FRET Probe Chembiochem : a European Journal of Chemical Biology. Sep, 2009 | Pubmed ID: 19637149 Interaction of Beta-amyloid(1-40) Peptide with Pairs of Metal Ions: An Electrospray Ion Trap Mass Spectrometric Model Study Biophysical Chemistry. Sep, 2009 | Pubmed ID: 19539421 Peptide Conjugates of Therapeutically Used Antitubercular Isoniazid-design, Synthesis and Antimycobacterial Effect Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2009 | Pubmed ID: 19319854 Matrix/analyte Ratio Influencing Polymer Molecular Weight Distribution in Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. May, 2009 | Pubmed ID: 19306286 Development of an Oxime Bond Containing Daunorubicin-gonadotropin-releasing Hormone-III Conjugate As a Potential Anticancer Drug Bioconjugate Chemistry. Apr, 2009 | Pubmed ID: 19296605 Synthesis and Antibody Recognition of Cyclic Epitope Peptides, Together with Their Dimer and Conjugated Derivatives Based on Residues 9-22 of Herpes Simplex Virus Type 1 Glycoprotein D Bioconjugate Chemistry. Apr, 2009 | Pubmed ID: 19271736 Synthesis of Hepcidin Derivatives in Order to Develop Standards for Immune Adsorption Method Journal of Peptide Science : an Official Publication of the European Peptide Society. Apr, 2009 | Pubmed ID: 19189268 Dual Labeling of Biomolecules by Using Click Chemistry: a Sequential Approach Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19065684 Design, Synthesis, and in Vitro Activity of Novel Drug Delivery Systems Containing Tuftsin Derivatives and Methotrexate Bioconjugate Chemistry. Nov, 2008 | Pubmed ID: 18959436 New Derivatives of GnRH As Potential Anticancer Therapeutic Agents Current Medicinal Chemistry. 2008 | Pubmed ID: 18855666 Effect of Conjugation with Polypeptide Carrier on the Enzymatic Degradation of Herpes Simplex Virus Glycoprotein D Derived Epitope Peptide Bioconjugate Chemistry. Aug, 2008 | Pubmed ID: 18651758 In Vitro Cytotoxicity, Chemotactic Effect, and Cellular Uptake of Branched Polypeptides with Poly[L-lys] Backbone by J774 Murine Macrophage Cell Line Bioconjugate Chemistry. May, 2008 | Pubmed ID: 18429626 Antibody Recognition and Conformational Flexibility of a Plaque-specific Beta-amyloid Epitope Modulated by Non-native Peptide Flanking Regions Journal of Medicinal Chemistry. Mar, 2008 | Pubmed ID: 18284185 Design, Structural, and Immuno-analytical Properties of Antigenic Bioconjugates Comprising a Beta-amyloid-plaque Specific Epitope Biopolymers. 2008 | Pubmed ID: 18183582 Synthesis and Antibody Recognition of Synthetic Antigens from MUC1 Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2008 | Pubmed ID: 17975847 Mass Spectrometric Identification of the Trypsin Cleavage Pathway in Lysyl-proline Containing Oligotuftsin Peptides Journal of Peptide Science : an Official Publication of the European Peptide Society. Apr, 2007 | Pubmed ID: 17394121 Structure, Enzymatic Stability and Antitumor Activity of Sea Lamprey GnRH-III and Its Dimer Derivatives Peptides. Apr, 2007 | Pubmed ID: 17254668 Disulfide Bond Rearrangement During Regioselective Oxidation in PhS(O)Ph/CH3SiCl3 Mixture for the Synthesis of Alpha-conotoxin GI Biopolymers. 2007 | Pubmed ID: 17063467 Influence of Sequential Oligopeptide Carriers on the Bioactive Structure of Conjugated Epitopes: Comparative Study of the Conformation of a Herpes Simplex Virus Glycoprotein GD-1 Epitope in the Free and Conjugated Form, and Protein "built-in" Crystal Structure Biopolymers. 2006 | Pubmed ID: 16493659 Synthesis of Oligotuftsin-based Branched Oligopeptide Conjugates for Chemotactic Drug Targeting Journal of Peptide Science : an Official Publication of the European Peptide Society. May, 2006 | Pubmed ID: 16245264 Synthesis of Linear, Branched, and Cyclic Peptide Chimera Methods in Molecular Biology (Clifton, N.J.). 2005 | Pubmed ID: 16044540 Synthesis, Solution Conformation, and Antibody Recognition of Oligotuftsin-based Conjugates Containing a Beta-amyloid(4-10) Plaque-specific Epitope Bioconjugate Chemistry. Jul-Aug, 2005 | Pubmed ID: 16029033 The Effect of Cyclization on the Enzymatic Degradation of Herpes Simplex Virus Glycoprotein D Derived Epitope Peptide Journal of Peptide Science : an Official Publication of the European Peptide Society. Oct, 2005 | Pubmed ID: 15864815 Synthesis and Structural Characterization of Bioactive Peptide Conjugates Using Thioether Linkage Approaches Journal of Peptide Science : an Official Publication of the European Peptide Society. Dec, 2004 | Pubmed ID: 15635622 Polypeptide Conjugates Comprising a Beta-amyloid Plaque-specific Epitope As New Vaccine Structures Against Alzheimer's Disease Biopolymers. 2004 | Pubmed ID: 15499564 Natively Unfolded Tubulin Polymerization Promoting Protein TPPP/p25 is a Common Marker of Alpha-synucleinopathies Neurobiology of Disease. Nov, 2004 | Pubmed ID: 15474353 In Vitro T-cell Immunogenicity of Oligopeptides Derived from the Region 92-110 of the 16-kDa Protein of Mycobacterium Tuberculosis Biopolymers. 2004 | Pubmed ID: 15386261 Synthesis, Conformation, and Immunoreactivity of New Carrier Molecules Based on Repeated Tuftsin-like Sequence Biopolymers. Apr, 2004 | Pubmed ID: 15048768 Modeling of Main Characteristics of Bullous Pemphigoid Antigen-2 (BPAG2) Peptide Structure in Serological Recognition by Autoantibodies Pathology Oncology Research : POR. 2004 | Pubmed ID: 15029263 Synthesis and Comparison of Antibody Recognition of Conjugates Containing Herpes Simplex Virus Type 1 Glycoprotein D Epitope VII Bioconjugate Chemistry. Nov-Dec, 2003 | Pubmed ID: 14624643 Degranulation and Superoxide Production Depend on Cholesterol in PLB-985 Cells Biochemical and Biophysical Research Communications. Oct, 2003 | Pubmed ID: 14559248 Synthesis, Solution Structure Analysis and Antibody Binding of Cyclic Epitope Peptides from Glycoprotein D of Herpes Simplex Virus Type I Biophysical Chemistry. Nov, 2003 | Pubmed ID: 14556904 Drug Targeting by Macromolecules Without Recognition Unit? Journal of Molecular Recognition : JMR. Sep-Oct, 2003 | Pubmed ID: 14523942 Monitoring Folding Transitions of Synthetic, Branched-chain Polypeptides by Capillary Zone Electrophoresis Electrophoresis. Mar, 2003 | Pubmed ID: 12627439 Mass Spectrometric and Chemical Stability of the Asp-Pro Bond in Herpes Simplex Virus Epitope Peptides Compared with X-Pro Bonds of Related Sequences Journal of Peptide Science : an Official Publication of the European Peptide Society. Aug, 2002 | Pubmed ID: 12212803 Peptide Based Vaccine Design: Synthesis and Immunological Characterization of Branched Polypeptide Conjugates Comprising the 276-284 Immunodominant Epitope of HSV-1 Glycoprotein D Journal of Peptide Science : an Official Publication of the European Peptide Society. Mar, 2002 | Pubmed ID: 11931583 I vitro Imaging och kvantifiering av det målsökande drog Effektivitet av fluorescerande GnRH-analoger József Murányi1,2, Attila Varga1, Bianka Gurbi1, Pál Gyulavári1, Gábor Mező3, Tibor Vántus2 1MTA-SE Pathobiochemistry Research Group, Semmelweis University, 2Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, 3MTA-ELTE Research Group of Peptide Chemistry, Eötvös Loránd University JoVE 55529 Cancer Research
I vitro Imaging och kvantifiering av det målsökande drog Effektivitet av fluorescerande GnRH-analoger József Murányi1,2, Attila Varga1, Bianka Gurbi1, Pál Gyulavári1, Gábor Mező3, Tibor Vántus2 1MTA-SE Pathobiochemistry Research Group, Semmelweis University, 2Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, 3MTA-ELTE Research Group of Peptide Chemistry, Eötvös Loránd University JoVE 55529 Cancer Research