Ryan C. Riddle Department of Orthopaedic Surgery Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Ryan C. Riddle has not added a biography. If you are Ryan C. Riddle and would like to personalize this page please email our Author Liaison for assistance. Publications VascuViz: a Multimodality and Multiscale Imaging and Visualization Pipeline for Vascular Systems Biology Nature Methods. 02, 2022 | Pubmed ID: 35145319 3D-printed Oxygen-releasing Scaffolds Improve Bone Regeneration in Mice Biomaterials. 01, 2022 | Pubmed ID: 34922272 Cellular and Tissue Crosstalk in Musculoskeletal Development Seminars in Cell & Developmental Biology. 03, 2022 | Pubmed ID: 34764024 Bone-derived Sclerostin and Wnt/β-catenin Signaling Regulate PDGFRα Adipoprogenitor Cell Differentiation FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 11, 2021 | Pubmed ID: 34606641 Maternal High-Fat Diet Induces Long-Lasting Defects in Bone Structure in Rat Offspring Through Enhanced Osteoclastogenesis Calcified Tissue International. 05, 2021 | Pubmed ID: 33386478 Dual Effects of Lipid Metabolism on Osteoblast Function Frontiers in Endocrinology. 2020 | Pubmed ID: 33071983 Preclinical Single Photon Emission Computed Tomography of Alpha Particle-Emitting Radium-223 Cancer Biotherapy & Radiopharmaceuticals. Sep, 2020 | Pubmed ID: 32182119 Frizzled-4 is Required for Normal Bone Acquisition Despite Compensation by Frizzled-8 Journal of Cellular Physiology. 10, 2020 | Pubmed ID: 31985040 CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 05, 2020 | Pubmed ID: 31808575 Precocious Chondrocyte Differentiation Disrupts Skeletal Growth in Kabuki Syndrome Mice JCI Insight. 10, 2019 | Pubmed ID: 31557133 The Role of Osteoblasts in Energy Homeostasis Nature Reviews. Endocrinology. 11, 2019 | Pubmed ID: 31462768 Heparin-Conjugated Decellularized Bone Particles Promote Enhanced Osteogenic Signaling of PDGF-BB to Adipose-Derived Stem Cells in Tissue Engineered Bone Grafts Advanced Healthcare Materials. 05, 2019 | Pubmed ID: 30941920 Lrp4 Expression by Adipocytes and Osteoblasts Differentially Impacts Sclerostin's Endocrine Effects on Body Composition and Glucose Metabolism The Journal of Biological Chemistry. 04, 2019 | Pubmed ID: 30842262 Regulation of Osteoblast Metabolism by Wnt Signaling Endocrinology and Metabolism (Seoul, Korea). Sep, 2018 | Pubmed ID: 30112869 β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice Endocrinology. 01, 2018 | Pubmed ID: 29077850 Fatty Acid Metabolism by the Osteoblast Bone. 10, 2018 | Pubmed ID: 28863948 Sclerostin Influences Body Composition by Regulating Catabolic and Anabolic Metabolism in Adipocytes Proceedings of the National Academy of Sciences of the United States of America. 12, 2017 | Pubmed ID: 29229807 Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism Endocrinology. 11, 2017 | Pubmed ID: 28938444 Fatty Acid Oxidation by the Osteoblast is Required for Normal Bone Acquisition in a Sex- and Diet-dependent Manner JCI Insight. Aug, 2017 | Pubmed ID: 28814665 Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance Cell Reports. 07, 2017 | Pubmed ID: 28723568 Ectopic Calcification in Pseudoxanthoma Elasticum Responds to Inhibition of Tissue-nonspecific Alkaline Phosphatase Science Translational Medicine. 06, 2017 | Pubmed ID: 28592560 Glucose Transporter-4 Facilitates Insulin-Stimulated Glucose Uptake in Osteoblasts Endocrinology. Nov, 2016 | Pubmed ID: 27689415 In Vivo Radiometric Analysis of Glucose Uptake and Distribution in Mouse Bone Bone Research. 2016 | Pubmed ID: 27088042 Whole-Body and Microenvironmental Localization of Radium-223 in Naïve and Mouse Models of Prostate Cancer Metastasis Journal of the National Cancer Institute. May, 2016 | Pubmed ID: 26683407 New Insights into the Biology of Osteocalcin Bone. Jan, 2016 | Pubmed ID: 26055108 Parathyroid Hormone Reprograms Osteoblast Metabolism Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Nov, 2015 | Pubmed ID: 26448640 Wnt-Lrp5 Signaling Regulates Fatty Acid Metabolism in the Osteoblast Molecular and Cellular Biology. Jun, 2015 | Pubmed ID: 25802278 Bone and the Regulation of Global Energy Balance Journal of Internal Medicine. Jun, 2015 | Pubmed ID: 25597336 Osteoblast Menin Regulates Bone Mass in Vivo The Journal of Biological Chemistry. Feb, 2015 | Pubmed ID: 25538250 Hypoxia-inducible Factor-1α Restricts the Anabolic Actions of Parathyroid Hormone Bone Research. 2014 | Pubmed ID: 26273518 Insulin, Osteoblasts, and Energy Metabolism: Why Bone Counts Calories The Journal of Clinical Investigation. Apr, 2014 | Pubmed ID: 24642463 Tsc2 is a Molecular Checkpoint Controlling Osteoblast Development and Glucose Homeostasis Molecular and Cellular Biology. May, 2014 | Pubmed ID: 24591652 Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts During Postnatal Bone Acquisition PloS One. 2013 | Pubmed ID: 23675479 BRMS1 Sensitizes Breast Cancer Cells to ATP-Induced Growth Suppression BioResearch Open Access. Apr, 2013 | Pubmed ID: 23593560 A Mouse Model for Human Osteogenesis Imperfecta Type VI Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2013 | Pubmed ID: 23413146 Hypoxia-inducible Factor-1α Protein Negatively Regulates Load-induced Bone Formation The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 22081627 Distinct Growth Hormone Receptor Signaling Modes Regulate Skeletal Muscle Development and Insulin Sensitivity in Mice The Journal of Clinical Investigation. Nov, 2010 | Pubmed ID: 20921627 Roles of Vessel Growth Factors in Bone Development and Repair Joint Bone Spine. Dec, 2010 | Pubmed ID: 20851027 Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition Cell. Jul, 2010 | Pubmed ID: 20655471 Role of HIF-1alpha in Skeletal Development Annals of the New York Academy of Sciences. Mar, 2010 | Pubmed ID: 20392254 Evaluation of Fatty Acid Oxidation in Cultured Bone Cells Soohyun P. Kim1, Zhu Li1, Ryan C. Riddle1,2 1Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, 2Research and Development Service, Baltimore Veterans Administration Medical Center JoVE 63638 Biology
Evaluation of Fatty Acid Oxidation in Cultured Bone Cells Soohyun P. Kim1, Zhu Li1, Ryan C. Riddle1,2 1Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, 2Research and Development Service, Baltimore Veterans Administration Medical Center JoVE 63638 Biology