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Screening of β2 Integrin Activation Inhibitors in Human Neutrophils
February 02, 2024
インテグリン阻害薬スクリーニングのためのフローサイトメトリーベースのハイスループット技術
00:45 min
•
384ウェルプレートフォーマットでヒト血液から単離された好中球を用いた化合物のハイスループットスクリーニング(英語)
02:35 min
•
フローサイトメトリーを用いた好中球スクリーニングアッセイ
01:03 min
•
Ziming Cao
,
Matthew J. Garcia
,
Larry A. Sklar
3,4,5
,
Angela Wandinger-Ness
4
,
Zhichao Fan
1
Department of Immunology, School of Medicine
,
UConn Health
,
2
Center for Molecular Discovery
,
University of New Mexico Health Sciences Center
,
3
Comprehensive Cancer Center
,
University of New Mexico Health Sciences Center
,
4
Department of Pathology
,
University of New Mexico Health Sciences Center
,
5
Autophagy, Inflammation, & Metabolism (AIM) Center
,
University of New Mexico
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このプロトコルは人間の好中球のβ2インテグリンの活発化を禁じる低分子薬剤を識別するために流れのcytometryベースの、ハイスループットのスクリーニング方法を記述する。
Article