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Adjunctive Exosome Therapy: Enhancing Myocardial Recovery Post-CABG Surgery

September 15th, 2023
1, 1, 2, 1, 1, 1, 3, 4,5, 1
1Department of Surgery, University of Minnesota, 2School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, 3Cardiology, Richmond VA Medical Center, 4Department of Research Service, Center for Veterans Research and Education, Veterans Affairs Health Care System, 5Department of Neuroscience, University of Minnesota

Summary
Automatic Translation

Denne studien presenterer en kirurgisk svinemodell av kronisk myokardiskemi på grunn av progredierende koronararteriestenose, noe som resulterer i nedsatt hjertefunksjon uten infarkt. Etter iskemi gjennomgår dyr off-pump koronar bypasstransplantat med epikardial plassering av stamceller-avledede eksosomer-laden kollagenplaster. Denne tilleggsbehandlingen forbedrer myokardfunksjonen og utvinningen.

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