1Department of Microbiology and Immunology, College of Medicine,National Cheng Kung University, 2Department of Dermatology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 3Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 4National Institute of Infectious Diseases and Vaccinology,National Health Research Institutes, 5Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 6Insititute of Basic Medical Sciences, College of Medicine,National Cheng Kung University, 7Department of Biochemistry and Molecular Biology, College of Medicine,National Cheng Kung University, 8Center of Applied Nanomedicine,National Cheng Kung University
Betydelsen av små kolonier för Candida spp. läkemedelsresistens har inte utforskats fullt ut. Antimikrobiell fotodynamisk terapi (aPDT) erbjuder en lovande strategi mot läkemedelsresistenta svampinfektioner. Denna studie visar att rosenbengalmedierad aPDT effektivt inaktiverar Candida glabrata och inducerar små kolonier, vilket utgör en unik procedur.
