Creating a Murine Model of RV Hypertrophy and Failure by Pulmonary Trunk Banding

June 14, 2024
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Summary

We describe a murine model of right ventricular pressure overload-induced by pulmonary trunk banding. Detailed protocols for intubation, surgery, and phenotyping by echocardiography are included in the paper. Custom-made instruments are used for intubation and surgery, allowing for fast and inexpensive reproduction of the model.