Christopher Grunseich Neurogenetics Branch, National Institute of Neurological Disorders and Stroke National Institutes of Health Biography Publications Institution JoVE Articles Christopher Grunseich has not added a biography. If you are Christopher Grunseich and would like to personalize this page please email our Author Liaison for assistance. Publications Molecular Pathogenesis of Spinal Bulbar Muscular Atrophy (Kennedy's Disease) and Avenues for Treatment Current Opinion in Neurology. 10, 2020 | Pubmed ID: 32773451 Intracellular Calcium Leak As a Therapeutic Target for RYR1-related Myopathies Acta Neuropathologica. 06, 2020 | Pubmed ID: 32236737 Clinical and Molecular Aspects of Senataxin Mutations in Amyotrophic Lateral Sclerosis 4 Annals of Neurology. 04, 2020 | Pubmed ID: 31957062 Radiation-induced Astrocyte Senescence is Rescued by Δ133p53 Neuro-oncology. 03, 2019 | Pubmed ID: 30615147 Safety, Tolerability, and Preliminary Efficacy of an IGF-1 Mimetic in Patients with Spinal and Bulbar Muscular Atrophy: a Randomised, Placebo-controlled Trial The Lancet. Neurology. 12, 2018 | Pubmed ID: 30337273 Transcription Factor-Mediated Differentiation of Human IPSCs into Neurons Current Protocols in Cell Biology. 06, 2018 | Pubmed ID: 29924488 Beyond Motor Neurons: Expanding the Clinical Spectrum in Kennedy's Disease Journal of Neurology, Neurosurgery, and Psychiatry. Aug, 2018 | Pubmed ID: 29353237 Charcot-Marie-Tooth Disease Type 4C: Novel Mutations, Clinical Presentations, and Diagnostic Challenges Muscle & Nerve. 05, 2018 | Pubmed ID: 28981955 Patient-identified Impact of Symptoms in Spinal and Bulbar Muscular Atrophy Muscle & Nerve. Jan, 2018 | Pubmed ID: 28877556 Nonalcoholic Fatty Liver Disease in Spinal and Bulbar Muscular Atrophy Neurology. Dec, 2017 | Pubmed ID: 29142082 A Defect in Myoblast Fusion Underlies Carey-Fineman-Ziter Syndrome Nature Communications. 07, 2017 | Pubmed ID: 28681861 Decreased Motor Neuron Support by SMA Astrocytes Due to Diminished MCP1 Secretion The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2017 | Pubmed ID: 28450545 Hippocampal Sclerosis and Mesial Temporal Lobe Epilepsy in Chorea-acanthocytosis: a Case with Clinical, Pathologic and Genetic Evaluation Neuropathology and Applied Neurobiology. 10, 2017 | Pubmed ID: 28398599 Adenylyl Cyclase Activating Polypeptide Reduces Phosphorylation and Toxicity of the Polyglutamine-expanded Androgen Receptor in Spinobulbar Muscular Atrophy Science Translational Medicine. 12, 2016 | Pubmed ID: 28003546 RNA-DNA Sequence Differences in Saccharomyces Cerevisiae Genome Research. 11, 2016 | Pubmed ID: 27638543 Spinal and Bulbar Muscular Atrophy Neurologic Clinics. Nov, 2015 | Pubmed ID: 26515625 A Randomized Controlled Trial of Exercise in Spinal and Bulbar Muscular Atrophy Annals of Clinical and Translational Neurology. Jul, 2015 | Pubmed ID: 26273686 A Functional Scale for Spinal and Bulbar Muscular Atrophy: Cross-sectional and Longitudinal Study Neuromuscular Disorders : NMD. Jul, 2015 | Pubmed ID: 25913211 Development of a Protein Marker Panel for Characterization of Human Induced Pluripotent Stem Cells (hiPSCs) Using Global Quantitative Proteome Analysis Stem Cell Research. May, 2015 | Pubmed ID: 25840413 Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia JAMA Neurology. May, 2015 | Pubmed ID: 25751282 Peripheral Neuropathy in a Family with Sandhoff Disease and SH3TC2 Deficiency Journal of Neurology. 2015 | Pubmed ID: 25736553 Protein Arginine Methyltransferase 6 Enhances Polyglutamine-expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy Neuron. Jan, 2015 | Pubmed ID: 25569348 Results of a Two-year Pilot Study of Clinical Outcome Measures in Collagen VI- and Laminin Alpha2-related Congenital Muscular Dystrophies Neuromuscular Disorders : NMD. Jan, 2015 | Pubmed ID: 25307854 Early Onset and Novel Features in a Spinal and Bulbar Muscular Atrophy Patient with a 68 CAG Repeat Neuromuscular Disorders : NMD. Nov, 2014 | Pubmed ID: 25047668 Stem Cell-derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients Neurobiology of Disease. Oct, 2014 | Pubmed ID: 24925468 RNA-DNA Differences Are Generated in Human Cells Within Seconds After RNA Exits Polymerase II Cell Reports. Mar, 2014 | Pubmed ID: 24561252 Cowchock Syndrome is Associated with a Mutation in Apoptosis-inducing Factor American Journal of Human Genetics. Dec, 2012 | Pubmed ID: 23217327 R-Loop Analysis by Dot-Blot Prisila Ramirez1, Robert J. Crouch2, Vivian G. Cheung1,3,4, Christopher Grunseich5 1Life Sciences Institute, University of Michigan, Ann Arbor, 2Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 3Department of Pediatrics, University of Michigan, Ann Arbor, 4Howard Hughes Medical Institute, 5Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health JoVE 62069 遗传学
R-Loop Analysis by Dot-Blot Prisila Ramirez1, Robert J. Crouch2, Vivian G. Cheung1,3,4, Christopher Grunseich5 1Life Sciences Institute, University of Michigan, Ann Arbor, 2Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 3Department of Pediatrics, University of Michigan, Ann Arbor, 4Howard Hughes Medical Institute, 5Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health JoVE 62069 遗传学