NSD, Oak Ridge National Laboratory 1 article published in JoVE Engineering Study of Protein Dynamics via Neutron Spin Echo Spectroscopy Laura-Roxana Stingaciu1 1NSD, Oak Ridge National Laboratory The present protocol describes methods for investigating the structure and dynamics of two model proteins that have an important role in human health. The technique combines bench-top biophysical characterization with neutron spin echo spectroscopy to access the dynamics at time and length scales relevant for protein interdomain motions.