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In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur
 

In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur

Article DOI: 10.3791/56679-v • 07:33 min • November 14th, 2017
November 14th, 2017 •
1, 1,4, 2, 3, 1, 4, *3, *1
1Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, 2RISystem, 3Core Facility Small Animal MRI, University Medical Center Ulm, 4Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, University Medical Center Ulm
* These authors contributed equally

章节

总结概括
Automatic Translation

The evaluation of tissue development in the fracture callus during endochondral bone healing is essential to monitor the healing process. Here, we report the use of a magnetic resonance imaging (MRI)-compatible external fixator for the mouse femur to allow MRI scans during bone regeneration in mice.

Tags

MRI-compatible Osteosynthesis Device Fracture Callus Development Bone Healing Mice Longitudinal Evaluation Magnetic Resonant Imaging Mouse Models External Fixator In Vivo Monitoring Real-time Standardized Fracture Healing Model Small Animal Imaging Core Facility Sedation Antibiotics Surgical Procedure
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