Antonio Musarò Institute Pasteur Cenci-Bolognetti, DAHFMO-Unit of Histology and Medical Embryology Sapienza University of Rome Biography Publications Institution JoVE Articles Antonio Musarò has not added a biography. If you are Antonio Musarò and would like to personalize this page please email our Author Liaison for assistance. Publications Oxidative Stress in Duchenne Muscular Dystrophy: Focus on the NRF2 Redox Pathway Human Molecular Genetics. May, 2017 | Pubmed ID: 28472288 Skeletal Muscle Myopenia in Mice Model of Bile Duct Ligation and Carbon Tetrachloride-induced Liver Cirrhosis Physiological Reports. Apr, 2017 | Pubmed ID: 28364027 Isolation and Culture of Satellite Cells from Mouse Skeletal Muscle Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28229414 Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy Stem Cells (Dayton, Ohio). Mar, 2017 | Pubmed ID: 27612437 FES in Europe and Beyond: Current Translational Research European Journal of Translational Myology. Sep, 2016 | Pubmed ID: 28078074 Stem Cells and Tissue Niche: Two Faces of the Same Coin of Muscle Regeneration European Journal of Translational Myology. Sep, 2016 | Pubmed ID: 28078070 Physical Exercise in Aging Human Skeletal Muscle Increases Mitochondrial Calcium Uniporter Expression Levels and Affects Mitochondria Dynamics Physiological Reports. Dec, 2016 | Pubmed ID: 28039397 Noise Enhances Action Potential Generation in Mouse Sensory Neurons Via Stochastic Resonance PloS One. 2016 | Pubmed ID: 27525414 Progressive Impairment of CaV1.1 Function in the Skeletal Muscle of Mice Expressing a Mutant Type 1 Cu/Zn Superoxide Dismutase (G93A) Linked to Amyotrophic Lateral Sclerosis Skeletal Muscle. 2016 | Pubmed ID: 27340545 Akt/mTOR Pathway Contributes to Skeletal Muscle Anti-atrophic Effect of Aerobic Exercise Training in Heart Failure Mice International Journal of Cardiology. Jul, 2016 | Pubmed ID: 27060274 A DIC Based Technique to Measure the Contraction of a Skeletal Muscle Engineered Tissue Applied Bionics and Biomechanics. 2016 | Pubmed ID: 27034612 Molecular and Cellular Mechanisms of Muscle Aging and Sarcopenia and Effects of Electrical Stimulation in Seniors European Journal of Translational Myology. Aug, 2015 | Pubmed ID: 26913161 Muscle Expression of SOD1(G93A) Modulates MicroRNA and MRNA Transcription Pattern Associated with the Myelination Process in the Spinal Cord of Transgenic Mice Frontiers in Cellular Neuroscience. 2015 | Pubmed ID: 26648847 Correction: Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential PloS One. 2015 | Pubmed ID: 26495969 Postmitotic Expression of SOD1(G93A) Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation Mediators of Inflammation. 2015 | Pubmed ID: 26491230 SAM68 is a Physiological Regulator of SMN2 Splicing in Spinal Muscular Atrophy The Journal of Cell Biology. Oct, 2015 | Pubmed ID: 26438828 Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential PloS One. 2015 | Pubmed ID: 26375957 Finite Mixture Clustering of Human Tissues with Different Levels of IGF-1 Splice Variants MRNA Transcripts BMC Bioinformatics. Sep, 2015 | Pubmed ID: 26370240 The Proteolytic Systems of Muscle Wasting Recent Advances in DNA & Gene Sequences. 2015 | Pubmed ID: 26361781 Increased Levels of Interleukin-6 Exacerbate the Dystrophic Phenotype in Mdx Mice Human Molecular Genetics. Nov, 2015 | Pubmed ID: 26251044 Functional and Morphological Improvement of Dystrophic Muscle by Interleukin 6 Receptor Blockade EBioMedicine. Apr, 2015 | Pubmed ID: 26137572 MicroRNAs Modulated by Local MIGF-1 Expression in Mdx Dystrophic Mice Frontiers in Aging Neuroscience. 2015 | Pubmed ID: 25999854 Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2015 | Pubmed ID: 25896247 Muscle IGF-1-induced Skeletal Muscle Hypertrophy Evokes Higher Insulin Sensitivity and Carbohydrate Use As Preferential Energy Substrate BioMed Research International. 2015 | Pubmed ID: 25722973 Proliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute P21 Suppression Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2015 | Pubmed ID: 25669433 Measuring Neuromuscular Junction Functionality in the SOD1(G93A) Animal Model of Amyotrophic Lateral Sclerosis Annals of Biomedical Engineering. Sep, 2015 | Pubmed ID: 25631208 New Insights into the Relationship Between MIGF-1-induced Hypertrophy and Ca2+ Handling in Differentiated Satellite Cells PloS One. 2014 | Pubmed ID: 25229238 Electrical Stimulation Counteracts Muscle Decline in Seniors Frontiers in Aging Neuroscience. 2014 | Pubmed ID: 25104935 IL-6 Impairs Myogenic Differentiation by Downmodulation of P90RSK/eEF2 and MTOR/p70S6K Axes, Without Affecting AKT Activity BioMed Research International. 2014 | Pubmed ID: 24967341 Involvement of MicroRNAs in the Regulation of Muscle Wasting During Catabolic Conditions The Journal of Biological Chemistry. Aug, 2014 | Pubmed ID: 24891504 Long-term High-level Exercise Promotes Muscle Reinnervation with Age Journal of Neuropathology and Experimental Neurology. Apr, 2014 | Pubmed ID: 24607961 Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice PloS One. 2014 | Pubmed ID: 23755187 Increased Plin2 Expression in Human Skeletal Muscle is Associated with Sarcopenia and Muscle Weakness PloS One. 2013 | Pubmed ID: 23977392 Age-dependent Alteration in Muscle Regeneration: the Critical Role of Tissue Niche Biogerontology. Jun, 2013 | Pubmed ID: 23666344 Circulating Levels of Adipokines and IGF-1 Are Associated with Skeletal Muscle Strength of Young and Old Healthy Subjects Biogerontology. Jun, 2013 | Pubmed ID: 23666343 Generation of EX Vivo-vascularized Muscle Engineered Tissue (X-MET) Scientific Reports. 2013 | Pubmed ID: 23478253 A Necrotic Stimulus is Required to Maximize Matrix-mediated Myogenesis in Mice Disease Models & Mechanisms. May, 2013 | Pubmed ID: 23471914 Understanding ALS: New Therapeutic Approaches The FEBS Journal. Sep, 2013 | Pubmed ID: 23217177 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy Autophagy. Apr, 2012 | Pubmed ID: 22966490 To the Heart of the Problem. MIGF-1: Local Effort for Global Impact Aging. Jun, 2012 | Pubmed ID: 22728569 IPLEX Administration Improves Motor Neuron Survival and Ameliorates Motor Functions in a Severe Mouse Model of Spinal Muscular Atrophy Molecular Medicine (Cambridge, Mass.). Sep, 2012 | Pubmed ID: 22669476 Adaptation of Mouse Skeletal Muscle to Long-term Microgravity in the MDS Mission PloS One. 2012 | Pubmed ID: 22470446 Exploiting Extracellular Matrix-stem Cell Interactions: a Review of Natural Materials for Therapeutic Muscle Regeneration Biomaterials. Jan, 2012 | Pubmed ID: 22014942 Atrophy/hypertrophy Cell Signaling in Muscles of Young Athletes Trained with Vibrational-proprioceptive Stimulation Neurological Research. Dec, 2011 | Pubmed ID: 22196751 Human Cardiac Progenitor Cell Grafts As Unrestricted Source of Supernumerary Cardiac Cells in Healthy Murine Hearts Stem Cells (Dayton, Ohio). Dec, 2011 | Pubmed ID: 22009661 Skeletal Muscle Regeneration in Mice is Stimulated by Local Overexpression of V1a-vasopressin Receptor Molecular Endocrinology (Baltimore, Md.). Sep, 2011 | Pubmed ID: 21816902 Muscle Atrophy Induced by SOD1G93A Expression Does Not Involve the Activation of Caspase in the Absence of Denervation Skeletal Muscle. Jan, 2011 | Pubmed ID: 21798081 Increased IGF-1 in Muscle Modulates the Phenotype of Severe SMA Mice Human Molecular Genetics. May, 2011 | Pubmed ID: 21325354 Impact of Ageing on Muscle Cell Regeneration Ageing Research Reviews. Jan, 2011 | Pubmed ID: 19683075 State of the Art and the Dark Side of Amyotrophic Lateral Sclerosis World Journal of Biological Chemistry. May, 2010 | Pubmed ID: 21540991 Regulation of Muscle Atrophy in Aging and Disease Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20886766 MicroRNAs Involved in Molecular Circuitries Relevant for the Duchenne Muscular Dystrophy Pathogenesis Are Controlled by the Dystrophin/nNOS Pathway Cell Metabolism. Oct, 2010 | Pubmed ID: 20727829 Comments on Point:Counterpoint: IGF Is/is Not the Major Physiological Regulator of Muscle Mass. The Strange Case of IGF-1 Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2010 | Pubmed ID: 20527694 Isolation and Culture of Mouse Satellite Cells Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20204623 Induction of Myogenic Differentiation by SDF-1 Via CXCR4 and CXCR7 Receptors Muscle & Nerve. Jun, 2010 | Pubmed ID: 20151462 Oxidative Stress and Muscle Homeostasis Current Opinion in Clinical Nutrition and Metabolic Care. May, 2010 | Pubmed ID: 20098320 Counteracting Muscle Wasting in Aging and Neuromuscular Diseases: the Critical Role of IGF-1 Aging. May, 2009 | Pubmed ID: 20157530 Flavocoxid Counteracts Muscle Necrosis and Improves Functional Properties in Mdx Mice: a Comparison Study with Methylprednisolone Experimental Neurology. Dec, 2009 | Pubmed ID: 19786019 Mechanical Properties of Intact Single Fibres from Wild-type and MLC/mIgf-1 Transgenic Mouse Muscle Journal of Muscle Research and Cell Motility. 2009 | Pubmed ID: 19731048 Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy Neuron. Aug, 2009 | Pubmed ID: 19679072 Muscle Involvement and IGF-1 Signaling in Genetic Disorders: New Therapeutic Approaches Endocrine Development. 2009 | Pubmed ID: 19293573 Localized Accumulation of Oxidative Stress Causes Muscle Atrophy Through Activation of an Autophagic Pathway Autophagy. May, 2009 | Pubmed ID: 19221466 Skeletal Muscle is a Primary Target of SOD1G93A-mediated Toxicity Cell Metabolism. Nov, 2008 | Pubmed ID: 19046573 Cdk9-55: a New Player in Muscle Regeneration Journal of Cellular Physiology. Sep, 2008 | Pubmed ID: 18546201 Long-term Benefit of Adeno-associated Virus/antisense-mediated Exon Skipping in Dystrophic Mice Human Gene Therapy. Jun, 2008 | Pubmed ID: 18500943 Measuring Mechanical Properties, Including Isotonic Fatigue, of Fast and Slow MLC/mIgf-1 Transgenic Skeletal Muscle Annals of Biomedical Engineering. Jul, 2008 | Pubmed ID: 18415017 Local Expression of MIgf-1 Modulates Ubiquitin, Caspase and CDK5 Expression in Skeletal Muscle of an ALS Mouse Model Neurological Research. Mar, 2008 | Pubmed ID: 18397603 ROCK2 and Its Alternatively Spliced Isoform ROCK2m Positively Control the Maturation of the Myogenic Program Molecular and Cellular Biology. Sep, 2007 | Pubmed ID: 17606625 Hypertrophy and Atrophy Inversely Regulate Caveolin-3 Expression in Myoblasts Biochemical and Biophysical Research Communications. May, 2007 | Pubmed ID: 17418092 Local Expression of IGF-1 Accelerates Muscle Regeneration by Rapidly Modulating Inflammatory Cytokines and Chemokines FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2007 | Pubmed ID: 17264161 The Neuroprotective Effects of a Locally Acting IGF-1 Isoform Experimental Gerontology. Jan-Feb, 2007 | Pubmed ID: 16782294 Growth Factor Enhancement of Cardiac Regeneration Cell Transplantation. 2006 | Pubmed ID: 16826794 Chimeric Adeno-associated Virus/antisense U1 Small Nuclear RNA Effectively Rescues Dystrophin Synthesis and Muscle Function by Local Treatment of Mdx Mice Human Gene Therapy. May, 2006 | Pubmed ID: 16716113 Body-wide Gene Therapy of Duchenne Muscular Dystrophy in the Mdx Mouse Model Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16501048 Vasopressin-dependent Myogenic Cell Differentiation is Mediated by Both Ca2+/calmodulin-dependent Kinase and Calcineurin Pathways Molecular Biology of the Cell. Aug, 2005 | Pubmed ID: 15930130 Muscle Expression of a Local Igf-1 Isoform Protects Motor Neurons in an ALS Mouse Model The Journal of Cell Biology. Jan, 2005 | Pubmed ID: 15657392 Stem Cell-mediated Muscle Regeneration is Enhanced by Local Isoform of Insulin-like Growth Factor 1 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14745025 Gene Therapy for Cardiac Cachexia? International Journal of Cardiology. Sep, 2002 | Pubmed ID: 12163223 AVP Induces Myogenesis Through the Transcriptional Activation of the Myocyte Enhancer Factor 2 Molecular Endocrinology (Baltimore, Md.). Jun, 2002 | Pubmed ID: 12040025 Muscle-specific Expression of Insulin-like Growth Factor I Counters Muscle Decline in Mdx Mice The Journal of Cell Biology. Apr, 2002 | Pubmed ID: 11927606 Measuring Neuromuscular Junction Functionality Emanuele Rizzuto1, Simona Pisu2, Carmine Nicoletti2, Zaccaria Del Prete1,3, Antonio Musarò2,3 1Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 2Institute Pasteur Cenci-Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, 3Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia JoVE 55227 Neurowissenschaften
Measuring Neuromuscular Junction Functionality Emanuele Rizzuto1, Simona Pisu2, Carmine Nicoletti2, Zaccaria Del Prete1,3, Antonio Musarò2,3 1Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 2Institute Pasteur Cenci-Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, 3Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia JoVE 55227 Neurowissenschaften