Investigating Physiological Responses to Acute Volume Overload in Porcine Models

January 12, 2024

Adult and Pediatric Porcine Model of Acute Volume Overload

Bret D. Alvis², Jenna Helmer Sobey, Lexie Vaughn, Christina Jelly, Dawson Wervey, Joyce Cheung-Flynn, Marisa Case, Colleen Brophy, Kyle Hocking³

¹Department of Anesthesiology,Vanderbilt University Medical Center, ²Department of Biomedical Engineering,Vanderbilt University, ³Department of Surgery,Vanderbilt University Medical Center, ⁴Ohio University Heritage College of Osteopathic Medicine

Summary

The protocol here shows how continuous administration of crystalloids into the central veins of a euvolemic pig/piglet allows for the appropriate investigation of the physiological effects of acute volume overload.

Investigating Physiological Responses to Acute Volume Overload in Porcine Models

Adult and Pediatric Porcine Model of Acute Volume Overload

Summary

Article