University of Antwerp - imec 1 article published in JoVE Biochemistry Design and Construction of an Experimental Setup to Enhance Mineral Weathering through the Activity of Soil Organisms Tullia Calogiuri1,2, Mathilde Hagens2, Jan Willem Van Groenigen1, Thomas Corbett3, Jens Hartmann4, Rick Hendriksen5, Iris Janssens6, Ivan A. Janssens7, Guillermo Ledesma Dominguez7, Grant Loescher4, Steven Mortier6, Anna Neubeck3, Harun Niron7, Reinaldy P. Poetra4, Lukas Rieder4, Eric Struyf7, Michiel Van Tendeloo8, Tom De Schepper6, Tim Verdonck9, Siegfried E. Vlaeminck8, Sara Vicca7, Alix Vidal1 1Soil Biology Group, Wageningen University & Research, 2Soil Chemistry and Chemical Soil Quality, Wageningen University & Research, 3Department of Earth Sciences, Uppsala University, 4Institute for Geology, Center for Earth System Research and Sustainability, University of Hamburg, 5Tupola, Wageningen University & Research, 6IDLab - Department of Computer Science, University of Antwerp - imec, 7Plants and Ecosystems (PLECO), Biology Department, University of Antwerp, 8Research Group of Sustainable Energy, Air and Water Technology, University of Antwerp, 9Department of Mathematics, University of Antwerp - imec Here we present the construction and operation of an experimental setup to enhance mineral weathering through the activity of soil organisms while concurrently manipulating abiotic variables known to stimulate weathering. Representative results from the functioning of the setup and sample analyses are discussed together with points for improvement.