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High-throughput Screening and Biosensing with Fluorescent C. elegans Strains
 
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High-throughput Screening and Biosensing with Fluorescent C. elegans Strains

Article DOI: 10.3791/2745-v • 14:53 min • May 19th, 2011
May 19th, 2011 •
1, 1, 2, 1
1Department of Biology, University of Florida, 2Mount Desert Island Biological Laboratory

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A procedure for liquid-based culturing and dispensing of C. elegans strains expressing fluorescent reporter proteins is described that does not require expensive sorting equipment. This approach can be applied to numerous inducible C. elegans genes for drug discovery or biosensing of contaminants.

Tags

High-throughput Screening Biosensing Fluorescent C. Elegans Strains Chemical Modulators Biological Processes Cell Culture Models In Vivo Screening Whole Animal Models Drug Development C. Elegans As A Model Organism Drug Mode-of-action Identification Culturing And Dispensing Protocol High-throughput Screening Of Chemical Libraries Detection Of Environmental Contaminants Gene Expression Alteration Fluorescence Microplate Reader
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