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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
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Biologie
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JoVE Journal Biologie
Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs

DOI:
10.3791/63995-v

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08:18 min

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July 27, 2022

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, , , ,
1Department of Pharmacy,Quaid-i-Azam University, 2Department of Pharmaceutics, Faculty of Pharmacy,The Islamia University of Bahawalpur, 3Nazar College of Pharmacy

Kapitel

  • 00:00Introduction
  • 01:08Screening of the Oils, Surfactants, and Cosurfactants
  • 02:40Construction of the Pseudo Ternary Phase Diagram
  • 03:16Optimization via Software Using a Response Surface Methodology
  • 04:27Characterization
  • 05:07In Vitro Dissolution Studies
  • 05:49Results: Exploring the Potential of Omega-3 Fatty Acids-Rich Oil to Act as Drug Carriers
  • 07:30Conclusion

Summary

Automatische Übersetzung

Automatische Übersetzung

Oils used for drug delivery applications can disrupt the lipid profile of patients, which is undesirable in cardiovascular diseases. Omega-3 fatty acids-rich oils are a healthy alternative to conventional oils and have enormous potential for self-emulsified drug delivery systems.

Tags

Self-nanoemulsificationOmega-3 Fatty AcidsLipophilic DrugsRosuvastatinSNEDDSSolubility EnhancementResponse Surface MethodologyBox-Behnken DesignFish OilTween 80Capryol PGMC

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