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Enhancing Targeted Cancer Diagnosis by Quantifying Single-Cell Mechanics

May 19, 2023
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Shear Assay Protocol for the Determination of Single-Cell Material Properties

02:25 min
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Microfluidic Shear Apparatus Setup for Single-Cell Fluid Shear Assay

02:16 min
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Performing Single-Cell Shear Assay and Imaging

01:51 min
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Processing the Single-Cell Shear Assay Imaging Data

02:11 min
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1Department of Aerospace and Mechanical Engineering,University of Notre Dame, 2Departments of Mechanical and Biomedical Engineering,Worcester Polytechnic Institute

Summary

Traducción Automática

This protocol outlines the quantification of the mechanical properties of cancerous and non-cancerous cell lines in vitro. Conserved differences in the mechanics of cancerous and normal cells can act as a biomarker that may have implications in prognosis and diagnosis.

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