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Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures
 

Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures

Article DOI: 10.3791/2949-v • 16:02 min • August 1st, 2011
August 1st, 2011 •
1, 1, 1, 1, 1, 1
1Section on Critical Brain Dynamics, National Institute of Mental Health

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A robust way to study neuronal avalanches, i.e. scale-invariant spatio-temporal activity bursts, indicative of critical state dynamics in cortex. Avalanches emerge spontaneously in developing superficial layers of cultured cortex which allows for long-term measurements of the activity with planar integrated multi-electrode arrays (MEA) under precisely controlled conditions.

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Multi-electrode Array Recordings Neuronal Avalanches Organotypic Cultures Cortex Activity Ongoing Activity Spontaneous Activity Migration Of Cortex Cell Types Formation Of Neuronal Connections Sensory Stimuli Integration Cortex Function Recording Techniques Local Field Potential (LFP) Extracellular Microelectrodes Electroencephalogram (EEG) Magnetoencephalogram (MEG) BOLD Signal Functional Magnetic Resonance Imaging (fMRI) Mesoscopic Scale Synchronized Activities Deflections In LFP Array Of Microelectrodes
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