Waiting
Procesando inicio de sesión ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Bioluminescence Imaging of NADPH Oxidase Activity …
JoVE Journal
Immunology and Infection

Se requiere una suscripción a JoVE para ver este contenido. Inicie sesión o comience su prueba gratuita.

JoVE Journal Immunology and Infection
Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models
 

Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models

Article DOI: 10.3791/3925-v • 10:42 min • October 22nd, 2012
October 22nd, 2012 •
1, 1, 2,3, 1
1Department of Medicine, Vanderbilt University School of Medicine, 2Departments of Medicine and Immunology, Roswell Park Cancer Institute, 3Department of Medicine, University at Buffalo School of Medicine

Capítulos

Resumen
Automatic Translation

NADPH oxidase is the major source of reactive oxygen species (ROS) in phagocytes. Because of the ephemeral nature of ROS, it is difficult to measure and monitor ROS levels in living animals. A minimally invasive method for serial quantification of ROS in living mice is described.

Tags

Bioluminescence Imaging NADPH Oxidase Activity Animal Models Antibacterial Defense Antifungal Defense Inflammatory Response Real-time Kinetics ROS Generation Research Tool Host Defense Inflammation Injury Chronic Granulomatous Disease CGD Inherited Disorder NADPH Oxidase Components Gp91phox-deficient Mice P47phox-deficient Mice Impaired Host Defense Phagocytes Isoforms Of NADPH Oxidase Quantify ROS Production Models Of Inflammation And Injury
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter