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Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice
 

Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice

Article DOI: 10.3791/53076-v • 06:22 min • September 17th, 2015
September 17th, 2015 •
1, 1, 1
1Pharmakologisches Institut, Universität Heidelberg

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Resumen
Automatic Translation

Murine left ventricular papillary muscle can be used to investigate cardiac contractility in vitro. This article describes in detail the isolation and experimental protocols to study cardiac contractile characteristics.

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Contractility Measurements Isolated Papillary Muscles Cardiac Inotropy Mice Physiological Conditions Pathological Conditions Contractile Characteristics Vascular Tonus Neurohumoral Status Scientific Approach Single Cell Measurements Cardiac Myocytes In Vivo Studies Echocardiography Papillary Muscle Preparations Cardiac Physiology/pathophysiology Pharmacological Agents Transgenic Animal Models Organ Bath Setup Murine Left Anterior Papillary Muscle Muscle Strip Preparation Ventricular Wall Muscle Tissue Damage Temperature-controlled Organ Bath Chambers Electric Stimulation Twitch Force Amplitude Twitch Kinetics
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