Biolayer Interferometry (BLI) for Evaluating PROTACS-Induced Ternary Complex Formation

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Biolayer Interferometry (BLI) for Evaluating PROTACS-Induced Ternary Complex Formation (Video) | JoVE

Published: January 12, 2024

doi:

10.3791/200655

Wei Jiang, Holly Soutter

¹Center for the Development of Therapeutics,The Broad Institute of MIT and Harvard

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Keywords: Biolayer Interferometry BLI PROTACS Ternary Complex Formation VHL MZ1 BRD4 Binary Complex Ternary Complex On Rate Off Rate Equilibrium Dissociation Constant

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Biolayer Interferometry (BLI) for Evaluating PROTACS-Induced Ternary Complex Formation. J. Vis. Exp. (Pending Publication), e200655, doi:10.3791/200655 (2024).

Biolayer Interferometry (BLI) for Evaluating PROTACS-Induced Ternary Complex Formation (Video) | JoVE

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