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Establishment of 3D Morphogenesis in a Canine IBD Gut-on-a-Chip System

February 09, 2024
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Development and Application of a Canine IBD Gut-on-a-Chip Model for 3D Intestinal Morphogenesis Studies (Video) | JoVE

01:58 min
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Surface Activation and Extracellular Matrix Coating of a PDMS-Based Gut-on-a-Chip Device (Video) | JoVE

02:38 min
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2D Monolayer Formation and 3D Morphogenesis Establishment in a Canine Gut-on-a-Chip System (Video) | JoVE

02:42 min
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1Department of Veterinary Clinical Sciences, College of Veterinary Medicine,Washington State University, 2Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences,The University of Tokyo

Summary

Traduction automatique

Integration of canine intestinal organoids and a Gut-on-a-Chip microfluidic system offers relevant translational models for human intestinal diseases. Protocols presented allow for 3D morphogenesis and dynamic in vitro modeling of the gut, aiding in the development of effective treatments for intestinal diseases in dogs and humans with One Health.

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