Establishment and Evaluation of a Rat Femoral Box: Cavity Defect Model

November 21, 2023

Author Spotlight: The Box-Cavity Cortical Approach for Enhanced Evaluation of Biomaterials and Bone Regeneration

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Rat Femoral Diaphysis Box-Cavity Creation

01:48 min
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1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases,West China Hospital of Stomatology, Sichuan University, 2Department of Endodontics,West China Hospital of Stomatology, Sichuan University

Summary

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Here, we present a protocol for creating a box-cavity defect in rat femoral diaphysis tissue. This model can assess biomaterial performance under biomechanical stress and explore mechanisms of bone regeneration related to intramembranous osteogenesis.

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