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In vivo Imaging and Therapeutic Treatments in an Orthotopic Mouse Model of Ovarian Cancer
Journal JoVE
Biologie
This content is Free Access.
Journal JoVE Biologie
In vivo Imaging and Therapeutic Treatments in an Orthotopic Mouse Model of Ovarian Cancer
DOI:

07:46 min

August 17, 2010

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Chapitres

  • 00:04Titre
  • 00:59Introduction
  • 01:20Intrabursal Injection
  • 03:54Administration of Therapeutic Drugs by Oral Gavage
  • 05:20In Vivo Imaging
  • 06:41Representative Results
  • 07:18Conclusion

Summary

Traduction automatique

Orthotopic animal models of ovarian cancer replicate better human disease and therefore enhance our understanding of cancer progression and tumor response to therapy. A mouse model receives an intrabursal injection of luciferase-expressing ovarian tumor cells. Treatment is administered via oral gavage. Tumor growth is monitored by in vivo imaging system.

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