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Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
Journal JoVE
Médecine
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Journal JoVE Médecine
Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI

DOI:
10.3791/2148-v

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14:55 min

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April 18, 2011

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, , ,
1Sensory Motor Performance Program,Rehabilitation Institute of Chicago, 2Department of Kinesiology and Nutrition,University of Illinois at Chicago, 3Department of Physical Therapy,University of Illinois at Chicago

Chapitres

  • 00:05Titre
  • 01:15Introduction
  • 02:15Clinical Assessment
  • 04:00Quantitative Static Assessments – Velocity Dependent Stretch Reflex
  • 07:17Quantitative Dynamic Assessments
  • 10:41Effects of Acute Oral Administration of SSRIs in Human SCI
  • 14:16Conclusion

Summary

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This video demonstrates modulation of reflex activity, volitional strength and ambulation through clinical and quantitative assessments in individuals with motor incomplete SCI as a result of acute oral administration of a serotonin reuptake inhibitor (SSRI).

Tags

Pharmacologically Induced AlterationsMotor FunctionHuman Incomplete SCISpinal Cord InjuryVolitional Motor ControlRecovery From SCILong Term RehabilitationWalking AbilityMotor Incomplete SCIResidual Descending PathwaysMotor ImpairmentsWeaknessAbnormal Involuntary Reflex ActivitySpasticitySpasmsWalking RecoveryAbnormal Motor ReflexesFunctional BenefitsPharmacological InterventionsPhysical InterventionsEmpirical DataNeuromodulatory AgentsMonoaminesSerotonin (5HT)Norepinephrine (NE)Walking BehaviorsAnimal Models Of SCI

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