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Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
Journal JoVE
Médecine
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Journal JoVE Médecine
Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

DOI:
10.3791/2737-v

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06:03 min

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July 12, 2011

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, , , , ,
1Conrad Jobst Vascular Research Laboratories, Section of Vascular Surgery,University of Michigan , 2Department of Pharmacology,University of Michigan

Chapitres

  • 00:05Titre
  • 01:12Procedure to Anesthetize Mice
  • 01:57Mouse Micro-surgery and Recovery
  • 04:16Representative Post-surgical Analyses
  • 05:39Conclusion: Surgical Precaution

Summary

Traduction automatique

Traduction automatique

The electrolytic induction of endothelial activation to the internal surface of the Inferior Vena Cava results in venous type thrombus formation due to endothelial activation and partial blood stasis, two components of Virchow's triad.

Tags

Electrolytic Inferior Vena Cava ModelEIMVenous ThrombosisAnimal ModelsDVT ResearchThrombus FormationThrombus ResolutionTherapeutic CompoundsPotential Therapeutic Antagonist CompoundsThrombosed VeinPartial StasisMajor VeinContinuous Blood FlowTherapeutic AgentsDynamic FashionSensitivityVenous Endothelial Cell ActivationLeukocyte MigrationVenous ThrombogenesisAnalytical Purposes

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