/
/
Isolierung von Fidelity Varianten von RNA-Viren und Charakterisierung von Virus-Mutation Frequency
This content is Free Access.
Chapitres
- 00:05Titre
- 01:54Determining Mutagen Toxicity for Cells
- 03:01Determining Mutagen Concentrations that Optimally Reduce Virus Titers
- 04:56Isolation and Identification of Mutagen Resistant Variants
- 06:41Confirming the Resistance Phenotype
- 08:32Checking Replication Rates and Measuring Mutation Frequencies
- 10:40Sequence Analysis
- 12:34Representative Results
- 17:27Conclusion
Tags
RNA VirusesFidelity VariantsVirus Mutation FrequencyRNA Dependent RNA PolymerasesExtreme Population DiversityVirus AdaptationVirus EvolutionIntrinsic Error RatesViral PolymeraseIncorporation FidelityMutation FrequenciesVirological TechniquesSequencing TechniquesStatistical SignificancePolymerase Structure And FunctionVirus Adaptation Mechanisms
