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Cannulation of the Mouse Submandibular Salivary Gland via the Wharton’s Duct
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Médecine
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Journal JoVE Médecine
Cannulation of the Mouse Submandibular Salivary Gland via the Wharton’s Duct

Cannulation of the Mouse Submandibular Salivary Gland via the Wharton’s Duct

DOI:
10.3791/3074-v

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05:18 min

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May 14, 2011

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, , , , , , ,
1Faculty of Dentistry,McGill University , 2National Institutes of Health, Bethesda, MD, USA

Chapitres

  • 00:00Titre
  • 00:18Introduction
  • 01:30Procédure
  • 03:46Representative Result
  • 04:05Discussion

Summary

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Traduction automatique

A protocol for the cannulation of the mouse submandibular salivary gland via the Wharton's duct is described. For this experiment, the trypan blue solution is used as a dyer to demonstrate how this technique effectively delivers infusions into the targeted gland, and to suggest the reliability of this new approach as a potential clinical drug/cell therapy for the regeneration of salivary glands.

Tags

CannulationMouse Submandibular Salivary GlandWharton’s DuctSevere Salivary Gland HypofunctionSjögren’s SyndromeTherapeutic IrradiationXerostomiaDysphagiaDental CariesAltered TasteOro-pharyngeal InfectionsMucositisRegenerative MedicineStem CellsGlandular CellsOrgan Function RevivalClinical Gene Transfer Application

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