Journal
/
Médecine
/
Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
Journal JoVE
Médecine
This content is Free Access.
Journal JoVE Médecine
Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

DOI:
10.3791/3107-v

•

11:24 min

•

October 18, 2011

•

, , , ,
1Department of Radiation Oncology,University of California Irvine

Chapitres

  • 00:05Titre
  • 01:43Radiotherapy: Treatment Planning and Irradiation
  • 04:51Surgery and Transplantation
  • 09:50Locating Transplanted Neural Stem Cells
  • 10:26Conclusion

Summary

Traduction automatique

Traduction automatique

Brain tumor patients routinely undergo cranial radiotherapy, and while beneficial, this treatment often results in debilitating cognitive dysfunction. This serious unresolved problem has at present, no clinical recourse, and has driven our efforts to devise stem cell based therapies for the recovery of radiation-induced cognitive decrements.

Tags

Stem Cell TransplantationCognitive DysfunctionCranial RadiotherapyBrain TumorsNeural Stem CellsRadiation-induced Cognitive DeclineAthymic Nude RatsHippocampusHuman Neural Stem Cells (hNSCs)Cognition ImprovementGrafted Cell SurvivalDifferentiation-specific Markers

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

check_url/fr/3107?article_type=v

Orthotopic Aortic Transplantation: A Rat Model to Study the Development of Chronic Vasculopathy
check_url/fr/3107?article_type=v

A Mouse Model of in Utero Transplantation
check_url/fr/3107?article_type=v

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
check_url/fr/3107?article_type=v

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model
check_url/fr/3107?article_type=v

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
check_url/fr/3107?article_type=v

Neural Stem Cell Transplantation in Experimental Contusive Model of Spinal Cord Injury
check_url/fr/3107?article_type=v

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies
check_url/fr/3107?article_type=v

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
check_url/fr/3107?article_type=v

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
check_url/fr/3107?article_type=v

Creation and Transplantation of an Adipose-derived Stem Cell (ASC) Sheet in a Diabetic Wound-healing Model

Read Article