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Endurance Training Protocol and Longitudinal Performance Assays for Drosophila melanogaster
Journal JoVE
Biologie
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Journal JoVE Biologie
Endurance Training Protocol and Longitudinal Performance Assays for Drosophila melanogaster

Endurance Training Protocol and Longitudinal Performance Assays for Drosophila melanogaster

DOI:
10.3791/3786-v

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09:49 min

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March 26, 2012

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, , ,
1Department of Geriatric Medicine,University of Michigan Medical School

Chapitres

  • 00:05Titre
  • 01:27Power Tower Setup and Operation
  • 03:03Running the Exercise Assay
  • 04:55Scoring Exercise and Locomotor Fatigue
  • 06:02Exercise, Age, and Locomotor Ability
  • 08:30Training Results
  • 09:22Conclusion

Summary

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We describe the first endurance training protocol for an important genetic model species, Drosophila melanogaster, and outline several assays to chart improvements in mobility following training.

Tags

Endurance Training ProtocolLongitudinal Performance AssaysDrosophila MelanogasterObesityDiabetesCardiovascular DiseaseEndurance ExerciseBeneficial InterventionExercise TrainingExcess Body Fat ReductionInsulin SensitivityAnti-inflammatory ResponsesAntioxidative ResponsesContractile Capacity ImprovementMitochondrial ActivityBiogenesisTranscriptional Coactivator PGC1-alphaAge-related DiseasesGenetic Model SpeciesGenetic ToolsDrosophila MaintenancePower Tower Apparatus

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