Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
Chapitres
- 00:05Titre
- 01:20Preparation of the Cells, Test Compounds and Cell Treatment
- 03:05Activation of GIRK Channels: Fluorescent Measurement and Analysis
- 04:10Results: Fluorescence Signal Measured using the GIRK Channel Assay
- 05:07Conclusion
Tags
Fluorescent Screening AssayModulatorsGIRK ChannelsG Protein-gated Inward Rectifier K+Cellular MediatorsHormonesNeurotransmittersBrainHeartSkeletal MuscleLigandsPlasma Membrane-bound ReceptorsG Protein-coupled Receptors (GPCRs)Stimulation Of G ProteinsGi And GoK+ Movement Out Of The CellResting Membrane PotentialNeuronsAction Potential FormationExcitatory NeurotransmittersHeart RateTherapeutic AgentsNeuropathic PainDrug AddictionCardiac ArrhythmiasPharmacologyAnti-arrhythmic AgentsAntipsychotic DrugsAntidepressants
