Journal
/
Biologie
/
A Novel Bayesiansk Change-point algoritme for Genome-wide analyse av Diverse ChIPseq Datatyper
Journal JoVE
Biologie
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Biologie
A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types

A Novel Bayesiansk Change-point algoritme for Genome-wide analyse av Diverse ChIPseq Datatyper

DOI:
10.3791/4273-v

•

12:39 min

•

December 10, 2012

•

, , ,
1Department of Applied Mathematics & Statistics,Stony Brook University, 2Computational Biology and Bioinformatics,Cold Spring Harbor Laboratory, 3Department of Molecular and Cell Biology,University of Texas at Dallas

Chapitres

  • 00:05Titre
  • 02:43Preprocessing: Preparing Input Files for Bayesian Change-point (BCP) Analysis & ChIP Read Densities for Detection of Enriched Islands in Diffuse Data
  • 04:48Estimating the Posterior Mean Read Density of Each Block using BCMIX Approximation
  • 06:24Post-processing Posterior Means of Diffuse Read Profiles
  • 07:06Results: Comparison of BCP and SICER in Analysis of Histone Modification Data
  • 11:47Conclusion

Summary

Traduction automatique

Traduction automatique

Vår Bayesiansk Endre Point (BCP) algoritme bygger på state-of-the-art fremskritt i modellering Change-poeng via Hidden Markov Models og bruker dem til kromatin immunoutfelling sekvensering (ChIPseq) dataanalyse. BCP fungerer godt i både brede og punctate datatyper, men utmerker seg i nøyaktig identifisere robuste, reproduserbare øyene diffuse histone berikelse.

Tags

Bayesian Change-point AlgorithmGenome-wide AnalysisChIPseq Data TypesProtein-DNA InteractionsRead Density ProfilesPeaksTranscription FactorsHistone ModificationsStatistical ModelsHidden Markov Models (HMMs)Ad Hoc ParametersResolutionUsabilityParameter Estimation ProceduresFinite State Classifications

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

check_url/fr/4273?article_type=v

Genome-wide Analysis of Aminoacylation (Charging) Levels of tRNA Using Microarrays
check_url/fr/4273?article_type=v

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets
check_url/fr/4273?article_type=v

Genome-wide Screen for miRNA Targets Bruke MISSION Target ID Library
check_url/fr/4273?article_type=v

To typer analyser for Oppdage Frog Sperm Chemoattraction
check_url/fr/4273?article_type=v

Kvantitative og Automated High-throughput Genome-wide RNAi skjermer i C. elegans</em
check_url/fr/4273?article_type=v

Genome-wide Gene Deletions in Streptococcus sanguinis by High Throughput PCR
check_url/fr/4273?article_type=v

Polysome fraksjonering og analyse av pattedyr Translatomes på en Genome-wide Scale
check_url/fr/4273?article_type=v

Genome-wide Kartlegging av narkotika DNA Interactions i Cells med COSMIC (Fornetting av små molekyler å isolere Chromatin)
check_url/fr/4273?article_type=v

Genome-wide Rensing av ekstrakromosomalt sirkulært DNA fra eukaryote celler
check_url/fr/4273?article_type=v

Omfattende arbeidsflyten for genomet-identifikasjon og uttrykk Meta-analyse av ATL E3 Ubiquitin Ligase Gene familien i Grapevine

Read Article