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Facial Transplants in Xenopus laevis Embryos
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Journal JoVE Biologie
Facial Transplants in Xenopus laevis Embryos

Facial Transplants in Xenopus laevis Embryos

DOI:
10.3791/50697-v

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09:08 min

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March 26, 2014

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, ,
1Biological Sciences in Dental Medicine,Harvard University, 2Biology Department,Massachusetts Institute of Technology, 3Whitehead Institute,Massachusetts Institute of Technology, 4Biology Department,Virginia Commonwealth University

Chapitres

  • 00:05Titre
  • 01:17Operation Preparation
  • 04:14Face Transplant Surgery
  • 06:28Face Transplant Post-operation Recovery
  • 07:31Results: Representative Facial Transplants
  • 08:39Conclusion

Summary

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Traduction automatique

A technique for transplanting "Extreme Anterior Domain" facial tissue between Xenopus laevis embryos has been developed. Tissue can be moved from one gene expression background into another, allowing the study of local requirements for craniofacial development and for signaling interactions between facial regions.

Tags

Facial TransplantsXenopus LaevisCraniofacial DevelopmentExtreme Anterior Domain (EAD)Chimeric FaceSignaling PathwaysLineage LabelEmbryosFrog ModelFacial RegionMicromanipulationDevelopmentHuman Relevance

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