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Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay
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Journal JoVE Chimie
Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay

Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay

DOI:
10.3791/50767-v

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11:14 min

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November 10, 2013

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, , , ,
1Institute of Chemistry,The Hebrew University of Jerusalem

Chapitres

  • 00:05Titre
  • 01:28Preparation of the Vanadium (V) and the Titanium (IV) Complexes
  • 02:55Preparation of HT-29 Cells in a 96-well Plate
  • 05:14Insertion of the Compounds
  • 07:05Cytotoxicity Measurement Using the MTT Assay
  • 08:37Results: Dose Dependent Cytotoxicity Curves
  • 10:47Conclusion

Summary

Traduction automatique

Traduction automatique

A method for synthesis of air-sensitive titanium and vanadium anticancer agents is described, along with the evaluation of their cytotoxic activity towards human cancer cell line by the MTT Assay.

Tags

Keywords: TitaniumVanadiumAnticancerMetal ComplexesSynthesisMTT AssayCytotoxicityHydrolytic InstabilityFormazanIC50Cell Viability

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