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PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
Journal JoVE
Bio-ingénierie
This content is Free Access.
Journal JoVE Bio-ingénierie
PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
DOI:

12:48 min

December 27, 2013

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Chapitres

  • 00:05Titre
  • 01:38Nanoparticle Preparation
  • 06:23Nanoparticle Collection
  • 09:07Sizing and Surface Morphology Using Scanning Electron Microscopy
  • 10:43Results: Particle Size Is Dependent on Emulsifier Concentration
  • 12:15Conclusion

Summary

Traduction automatique

We describe the production and characterization of nanoparticles and microparticles composed of poly(lactic-co-glycolic acid) using vitamin E-TPGS as an emulsifier. By varying formulation parameters such as the concentration of emulsifier, it is possible to produce nanoparticles with mean diameters ranging from 220 nm to 1.98 µm.

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