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Myocardial Infarction and Functional Outcome Assessment in Pigs
 

Myocardial Infarction and Functional Outcome Assessment in Pigs

Article DOI: 10.3791/51269-v • 12:03 min • April 25th, 2014
April 25th, 2014 •
1,2, 1, 1, 1, 1, 1, 1,2, 1,2, *1, *1
1Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 2Interuniversity Cardiology Institute of the Netherlands
* These authors contributed equally

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résumé
Automatic Translation

This protocol describes the porcine myocardial infarction (MI) model using a 90 min closed-chest coronary balloon occlusion of the left anterior descending artery (LAD), followed by reperfusion. Furthermore, the protocol for several outcome parameters, such as cardiac function, hemodynamics, microvascular resistance, and infarct size, are also presented.

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Keywords: Myocardial Infarction Porcine Model Closed-chest Coronary Balloon Occlusion Functional Outcome Assessment Cardiac Systolic And Diastolic Function Hemodynamics Coronary Flow Velocity Microvascular Resistance Infarct Size Cardioregenerative Biologics
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