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Inyección intraestriatal de sangre autóloga o clostridial colagenasa como modelos murinos de la hemorragia intracerebral
Journal JoVE
Médecine
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Journal JoVE Médecine
Intrastriatal Injection of Autologous Blood or Clostridial Collagenase as Murine Models of Intracerebral Hemorrhage
DOI:

09:41 min

July 03, 2014

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Chapitres

  • 00:05Titre
  • 01:58Preparations for Surgery
  • 02:54The Collagenase Injection Model
  • 04:54The Autologous Blood Injection Model
  • 06:48Post-operative Care
  • 07:25Hematoma Formation and Neurological Deficits of Injured Mice
  • 08:39Conclusion

Summary

Traduction automatique

Preclinical models of intracerebral hemorrhage are utilized to mimic certain aspects of clinical disease. Thus, mechanisms of injury and potential therapeutic strategies may be explored. In this protocol, two models of intracerebral hemorrhage are described, intrastriatal (basal ganglia) injections of autologous blood or collagenase.

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