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Automated Measurement of Microcirculatory Blood Flow Velocity in Pulmonary Metastases of Rats
 

Automated Measurement of Microcirculatory Blood Flow Velocity in Pulmonary Metastases of Rats

Article DOI: 10.3791/51630-v • 10:56 min • November 30th, 2014
November 30th, 2014 •
*1, *2, 2, 2, 2, 2, 2, 3, 2, 4
1Division of Plastic, Maxillofacial, and Oral Surgery, Duke University Medical Center, 2Department of Radiation Oncology, Duke University Medical Center, 3Department of Cardiology, University of Colorado Denver, 4Department of Physical Chemistry, University of Mainz
* These authors contributed equally

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résumé
Automatic Translation

A method is presented to measure microcirculatory blood flow velocity in pulmonary cancer metastases of the pleural surface in rats in an automated fashion, using closed-chest pulmonary intravital microscopy. This model has potential to be used as a widespread tool to perform physiologic research on pulmonary metastases in rodents.

Tags

Microcirculatory Blood Flow Pulmonary Metastases Intravital Microscopy Closed-chest Pulmonary Window Automated Blood Flow Velocity Analysis Pharmacological Intervention Tumor Vasculature
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