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Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
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Journal JoVE Biologie
Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants

DOI:
10.3791/51718-v

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09:16 min

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February 21, 2015

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, , ,
1Cytogenetics Department,Guy’s & St Thomas’ NHS Foundation Trust, 2Cytogenetics Department,Viapath Analytics

Chapitres

  • 00:05Titre
  • 01:13Labeling Reaction and Purification of DNA
  • 03:47Hybridization
  • 06:30Washing and Scanning Slides
  • 08:50Conclusion

Summary

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Traduction automatique

Array CGH for the detection of genomic copy number variants has replaced G-banded karyotype analysis. This paper describes the technology and its application in a diagnostic service laboratory.

Tags

Array CGHGenomic Copy Number VariantsDNA LabelingFluorochromesHybridizationOligonucleotide ProbesProbe DensityClinical Diagnostic ServiceGenome AnalysisCopy Number Detection

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