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Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor Growth.
Journal JoVE
Médecine
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Journal JoVE Médecine
Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor Growth.
DOI:

07:52 min

February 08, 2015

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Chapitres

  • 00:05Titre
  • 01:23Cell, Mouse, and Instrument Preparation
  • 02:34Orthotopic Injection
  • 04:19Organ Harvest
  • 05:39Results: Representative Othotopic and Metastatic Breast Tumor Growth in Mice
  • 07:25Conclusion

Summary

Traduction automatique

Cancer is a complex disease that is influenced by the tissue surrounding the tumor as well as local pro- and anti-inflammatory mediators. Therefore, orthotropic injection models, rather than subcutaneous models may be useful to study cancer progression in a manner that better mimics human pathology.

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