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El implante de gel de fibrina en pulmón de ratón para el Estudio de la angiogénesis pulmón específico
Journal JoVE
Médecine
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Journal JoVE Médecine
Implantation of Fibrin Gel on Mouse Lung to Study Lung-specific Angiogenesis
DOI:

07:52 min

December 21, 2014

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Chapitres

  • 00:05Titre
  • 01:13Fibrin Gel Preparation
  • 02:03Mouse Surgical Preparation
  • 03:25Fibrin Gel Placement
  • 05:04Harvesting the Lung
  • 06:12Results: Flourescence Micrographs of the Inside of Representative Lung Fibrin Gel Implants
  • 07:22Conclusion

Summary

Traduction automatique

Recapitulation of the organ-specific microenvironment, which stimulates local angiogenesis, is indispensable for successful regeneration of damaged tissues. This report demonstrates a novel method to implant fibrin gels on the lung surface of living mouse in order to explore how the lung-specific microenvironment modulates angiogenesis and alveolar regeneration in adult mouse.

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