Journal
/
/
Phenotyping माउस पल्मोनरी फंक्शन<em> Vivo</em> फेफड़े diffusing क्षमता के साथ
Journal JoVE
Biologie
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Biologie
Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity
DOI:

07:13 min

January 06, 2015

, , , , , ,

Chapitres

  • 00:05Titre
  • 01:18Setting up the Gas Chromotagraph
  • 02:24Measuring the Diffusion Factor for Carbon Monoxide (DFCO)
  • 04:46Results: Changes in DFCO in Different Pathologies
  • 06:39Conclusion

Summary

Traduction automatique

We describe a means to quickly and simply measure the lung diffusing capacity in mice and show that it is sufficiently sensitive to phenotype changes in multiple common lung pathologies. This metric thus brings direct translational relevance to the mouse models, since diffusing capacity is also easily measured in humans.

Vidéos Connexes

Read Article