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生きたマウスのシリアル内視鏡イメージングを使用して、腸の異常のための新しい治療の有効性の非侵襲的評価
Journal JoVE
Médecine
This content is Free Access.
Journal JoVE Médecine
Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
DOI:

09:01 min

March 10, 2015

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Chapitres

  • 00:05Titre
  • 02:02Pre-clinical Trial in an Epithelial Damage and Acute Colitis Model
  • 04:32Endoscope Examinations
  • 07:24Results: Acute DSS-induced Mucosal Damage
  • 08:25Conclusion

Summary

Traduction automatique

We describe methods for longitudinal monitoring of the efficacy of therapeutics for the treatment of colonic pathologies in mice using a rigid endoscope. This protocol can be readily used for the characterization of the therapeutic response of an individual tumor in live mice and also for monitoring potential disease relapse.

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