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Murine Modell av lårarteriens Wire Injury med Implantasjon av en perivaskulære Drug Delivery Patch
Journal JoVE
Médecine
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Journal JoVE Médecine
Murine Model of Femoral Artery Wire Injury with Implantation of a Perivascular Drug Delivery Patch
DOI:

07:05 min

February 10, 2015

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Chapitres

  • 00:05Titre
  • 01:24Femoral Artery Isolation
  • 03:00Femoral Artery Wire Injury, Arterial Closure, and Perivascular Drug Patch Implantation
  • 05:53Results: Representative Histological Results at 14 days Post Wire Injury
  • 06:26Conclusion

Summary

Traduction automatique

We describe a surgical technique that produces wire injury in the femoral artery of mice to induce neointimal hyperplasia to serve as a model testing system for the perivascular delivery of therapeutic compounds for the inhibition of restenosis.

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