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Onderzoek van Rapid Dopamine Dynamics met Fast scan cyclische voltammetrie Tijdens intra-orale Tastant Administration in Awake Rats
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1Interdepartmental Neuroscience Program,Yale University, 2Department of Biotechnical and Clinical Laboratory Sciences, School of Medicine and Biomedical Sciences,University at Buffalo, 3Department of Psychiatry,Yale School of Medicine, 4Department of Cellular and Molecular Physiology,Yale School of Medicine
Chapitres
- 00:05Titre
- 01:56Fabricating the Electrodes
- 04:14Fabricating Oral Catheters
- 05:24Combined Intraoral Surgery and Intracranial Cannulation Surgery
- 07:16Taking Voltametric Recordings in Awake, Freely Moving Rats
- 08:52Results: Tastant Stimulated Dopamine Release Measured in the NAc
- 10:11Conclusion
Rapid fluctuations in extracellular dopamine (DA) mediate both reward processing and motivated behavior in mammals. This manuscript describes the combined use of fast scan cyclic voltammetry (FSCV) and intra-oral tastant administration to determine how tastants alter rapid dopamine release in awake, freely moving rats.
